Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11937	Mitoxantrone	GSE70138	HME1	Human	3h	1.11uM	EID0016

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	ID2; KLF1; HES1; ID4; CTR9; BCLAF1; BAZ1B; ZMIZ2; EZH1; FOXF1; ZNF589; TBX2; PITX1; TAF11; ZNF580; DMTF1; MED25; BPTF; CIITA; RBBP7; MYBL2; LYL1; ARNTL; ASCL1; TAL1; RNF10; TSC22D3; FOXA2; MSX1; CCDC59; MEOX2; MYB; KLF9; DNAJC2; SSX1; IKZF1; TSG101; HMG20A; SMARCE1; CDK7; LHX6; BATF; ZMYND8; DDX5; FOSB; PBXIP1; RFXANK; ZNF274; HMGB1; RBBP8; PAX5; EZH2; TCF7; NEDD8; YBX2; KAT6B; AFF1; TADA3; RBBP4; SIAH2; AR; ZNF195; EGR1; STAT3; MDM2; BHLHE40; KLF5; HLTF; MED24; CRYM; TFCP2L1; RHOA; PSIP1; TCEB2; MYCL; SMARCA1; SAP18; SALL1; IRF4; FOXO1; KLF6; DLX5; HDAC9; SERTAD2; TCF4; PIR; MITF; SOX9; CITED2; NKX2-1; MNDA; IKBKAP; HTATIP2; EYA2; MKL2; NR2F1; ESR1; TRIM22; HMGA1; ZNF107; EGR2; LITAF; ID3; HMGN3; LEF1; TRPS1; FLNA; RBPMS; TXNIP; ID1
Down-regulation	105	FOSL1; FOSL2; MEF2C; HMGA2; MED17; MYC; MYCN; PREB; TFAP2A; HDAC4; ZNF175; CENPF; BLZF1; ADRB2; ZFP30; CEBPB; ZNF264; AHR; PURA; ZNF623; CREM; ST18; PEG3; USP22; BRWD1; WWC1; PPRC1; MYNN; ZNF112; KLF11; TMF1; ARNT2; WWP1; PBX3; ZMIZ1; VDR; MYBL1; TEAD4; ZNF268; PHF20; HOXA1; BANP; ELF4; ZNF141; INSM1; ZZZ3; MAFF; NKX3-1; ERG; RCOR1; ZBTB18; RBFOX2; CBX6; AGO2; MTDH; HOXD1; ZNF410; ZNF32; BAZ2B; ERBB4; ELK3; ZNF350; TULP4; IRF7; SHOX2; ZNF217; BTAF1; HIVEP1; TGIF2; PITX2; DLX2; NR4A3; ZNF606; BNC2; ZBED1; WNT4; FOXD1; PRPF6; MTF2; IRX5; HMG20B; ZNF423; TSC22D2; BCL3; MEIS2; ZNF232; SMAD1; CTBP2; FOXJ3; ZNF302; SCAND1; TRIM16; ETV5; LOXL2; TFAP2C; SOX11; ZEB1; WT1; ZBTB16; CREB1; ZFP36L2; SATB2; NKX2-2; ETS1; THAP11