Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11930 Chir-99021 GSE70138 HME1 Human 3h 3.33uM EID0016
Types Number Response transcription factors
Up-regulation 37 ASCL1; RLF; EDF1; RNF6; RBBP7; BRD2; TCF12; CRY1; DDIT3; NPM1; MLX; ISL1; ATF5; RNF138; ZBTB1; LEF1; VEZF1; CREB3L1; NRIP1; CTR9; TRIM32; HDAC1; TCEB2; SP3; SFPQ; RBBP8; SIAH2; FOXJ3; BAZ1A; HMGB2; HIC2; ZNF146; PIR; SATB2; THAP11; ID1; HOXC6
Down-regulation 60 TLE1; TCEA2; ARID5B; TFE3; KLF9; HBP1; ZEB1; PPP1R13L; SMAD4; PTRF; GON4L; SOX18; DBP; SPDEF; FOXN3; ZSCAN31; MED21; BACH1; ST18; TCF4; TGFB1; DNAJC1; TLE4; BASP1; NFE2; NCOA2; ZNF711; WNT4; IRF6; ZBED2; NR2F1; PAX6; CRYM; JUP; BCL11A; HLF; HOXB2; PNRC1; YAP1; MEIS1; STAT4; TFAP2C; TULP3; TXNIP; NR0B1; TRIP6; TFEC; TRIB3; ARNT2; ERG; PBX1; ZBTB20; EHF; WT1; RBPMS; EMX2; TWIST1; NFATC3; PEG3; IKZF1