Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11929 Chir-99021 GSE70138 HME1 Human 3h 10uM EID0016
Types Number Response transcription factors
Up-regulation 33 BHLHE40; CERS6; TCFL5; TOB1; MTF2; MAZ; IRX5; PLAGL1; SMARCA2; NR4A2; NRIP1; CTR9; SOX9; FOSB; SAP18; HLTF; MED24; PSIP1; ZNF91; RUNX1; MAGED1; SATB2; LEF1; EGR1; KLF4; EGR3; ATF3; ZNF107; KLF2; ZNF331; BCL11B; IRF6; FOXC1
Down-regulation 76 ADRB2; SOX4; MYCN; TRIM27; ZSCAN9; ELF4; HOXA5; BNC2; ZNF3; BRWD1; TFDP2; NFE2; ZFPM2; HOXB7; ZKSCAN7; TOX; TCF7L1; NFKB2; FOXO1; BRD8; TDP2; POU2AF1; TERF2; HOXB6; TGIF2; CTCF; EP300; VPS72; ZMIZ1; CUX2; ATF7IP; SOX2; RNF111; HOXD10; NRBF2; BACH2; CNOT6; TFAP2A; SPIB; HHEX; ZEB1; ZBTB16; ZHX2; CEBPD; ZNF544; TCF4; FOSL2; ZNF423; LMCD1; HOXB5; SOX13; SMAD1; SCAND1; SOX17; ZNF232; ZFP36L2; NEUROD1; KLF11; MYRF; ARNT2; HOXB2; SOX11; MEIS2; ZFP36L1; INSM1; BASP1; IRF8; TWIST1; NFATC4; ESR1; ZIC1; MEIS1; PBX1; TXNIP; MAFB; THAP11