Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11907 Torin-1 GSE70138 HME1 Human 3h 1.11uM EID0016
Types Number Response transcription factors
Up-regulation 52 SUV39H1; ARID5B; TSC22D3; TCFL5; PHF20; NR1D2; BTG1; RFX5; SATB1; RBM39; PNRC1; HIVEP2; YBX1; HDAC4; DDIT3; ITGB3BP; NR1H3; SMAD3; HBP1; RAD21; PMS1; IRF1; POU4F1; NFIL3; TBX3; BBX; BIRC2; ZBTB18; ID4; CITED2; KLF5; ZBTB38; KLF6; ELF1; KLF2; TGIF1; MXI1; SMARCA2; TXNIP; NRIP1; PEG3; HMGB2; ATF3; MYBL1; TSC22D1; MYB; CREB1; GATA6; LITAF; PBX3; LEF1; BASP1
Down-regulation 42 PBX2; RARA; ZFHX4; ZNF467; SIX3; SOHLH2; HMBOX1; TBX1; ZFHX3; MDM4; FOXF1; SIX2; EYA1; NR1H4; SHOX2; RUNX3; IRX4; TAL1; MDM2; SOX18; BATF; SOX11; IRF4; HIC2; ZNF512B; EMX2; SSX1; ZFP36L1; PITX1; HMGB3; HEY1; ZNF331; WT1; HOXC10; THAP11; SMAD1; ESR1; ARNT2; ASCL1; AEBP1; NFATC4; IKZF1