Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11906 Torin-1 GSE70138 HME1 Human 3h 3.33uM EID0016
Types Number Response transcription factors
Up-regulation 69 ARID5B; TSC22D3; ELF5; KLF2; TCFL5; SP140L; USF2; TBX2; MED15; NR1I2; BHLHE40; FOXO3; CITED2; BACH1; SOX4; FOXF2; POU3F2; NR2F1; TTF2; CREB3L2; BLM; ZMIZ2; FOXF1; CAMTA1; CDK7; RREB1; HBP1; MXI1; ZBTB43; ERBB4; STAT6; MKL2; ARID1A; SATB1; NR1D2; SMARCA2; SOX10; AES; FLNA; FOXC1; KDM5D; HMGB2; MLXIP; CUX1; LEF1; TGIF1; TXNIP; AFF1; PBXIP1; BMI1; JUNB; KLF4; SSX1; FLI1; WWTR1; BCL11B; NR4A2; ZNF107; MAGED1; NKX2-1; CARHSP1; CREB1; NRIP1; GATA6; SOX9; MAFB; LITAF; TOX3; HMG20B
Down-regulation 66 BCOR; CRK; TERF1; PPRC1; FOXK2; TGIF2; ZBED4; ENY2; MYCN; RNF111; VEZF1; C1QBP; ZNF45; ZBED2; SF1; ZNF394; PCGF3; HMGA2; WWP1; ZFHX4; ERF; GATA3; KLF11; ZNF532; CBFB; ZNF281; IRF7; SHOX2; MAF; ZNF516; MEOX1; HHEX; ATF5; SCAND1; ARNT2; SUPT4H1; TAL1; NAB1; RNF138; IRF8; TWIST1; TBL1X; BAZ1A; BCL3; ESR1; RUNX3; TCF4; ZNF232; ID1; MTF2; BRD4; HOXA10; NR2F6; NFATC4; WT1; HOXC10; PEG3; POU2AF1; SOX11; SMAD1; PBX1; THAP11; BASP1; NFATC3; E2F2; IKZF1