Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11896 Gsk-2126458 GSE70138 HME1 Human 3h 0.37uM EID0016
Types Number Response transcription factors
Up-regulation 43 TSC22D3; NFKBIA; SOX4; ARID5B; ID2; NCOA3; HOXA5; BTG1; CITED2; NFIL3; UBE2B; PNRC1; HBP1; HIVEP2; TAF12; BRD8; TSC22D1; CBX3; KLF4; KLF2; NR1D2; ZSCAN18; IRF7; KLF6; NRIP1; CREBL2; IRX5; PSIP1; CEBPD; ZNF165; ATF4; KLF10; RBPMS; MAFB; KLF5; TGIF1; FOSB; ATF3; TXNIP; HOXC6; TBX3; CREB1; PEG3
Down-regulation 29 PDLIM1; FOSL1; WDR77; CHD7; CBX6; SHOX2; TBL1X; TFEB; HOXA11; PLAGL2; SCAND1; TLE2; SIX2; PURA; PAX5; ZNF652; LEF1; CBFA2T3; ZNF512B; PBX3; ZFPM2; DACH1; ZNF91; EMX2; HOXA10; SOX11; MEIS1; HEY1; IKZF1