Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11879 Azd-7762 GSE70138 HME1 Human 3h 0.12uM EID0016
Types Number Response transcription factors
Up-regulation 40 FOSB; HOXA5; NR2C1; TRIP4; URI1; DEAF1; FOXM1; DNMT3B; ZNF131; IRX5; CBX3; CRY1; PMS1; EPAS1; PPARGC1A; FOS; BRD8; RBBP8; SATB1; ID3; PRKDC; TOB1; HTATIP2; TSC22D3; CTR9; LEF1; HLTF; TGIF1; FOXJ3; JUNB; NFIB; ZSCAN18; PBX3; ZNF165; CITED2; HMGA1; ID1; TRIM29; THAP11; MECOM
Down-regulation 81 NAB2; SP140; TGFB1I1; PAX9; POU4F1; BATF; DCC; ZNF14; AATF; ZNF267; NR4A3; PAX5; CAMTA1; HOXD11; ZNF124; NEUROD1; HLF; SOX3; FOXL2; ZNF248; ELF4; TBX21; ZNF175; ZNF345; SERTAD2; NR1H4; TAF1D; IRF1; BRWD1; ZNF334; IL16; SPIB; RYBP; EGR4; BNC2; INSM1; TFEC; SHOX2; POU2AF1; RNF138; ESRRG; FOSL2; APEX1; KAT2B; ZNF93; KLF10; RUNX3; FOXA1; MNDA; PCGF2; ZNF711; GATA6; MYCN; IRF9; OSR2; SOX11; LMCD1; BCL3; STAT4; ZIC3; NR2F1; ZNF91; HDAC9; MEOX1; HOXB6; TCF21; HIC2; CREB1; RBPJ; CBFA2T3; WT1; PRRX1; PAX6; NKX3-1; CD3D; KDM5D; EGR2; MEIS2; MAFB; NFATC3; IKZF1