Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11862 Azd-5438 GSE70138 HME1 Human 3h 0.04uM EID0016
Types Number Response transcription factors
Up-regulation 38 ID2; GATA2; ZNF672; ANKRD1; E2F2; ZNF274; RNF141; ZNF589; MAGED1; RUNX3; BMI1; PPARG; ID3; PIAS2; SALL1; FOXA2; KLF10; TAF4; EYA2; BHLHE40; PIR; SMAD7; ZBTB18; JUNB; JARID2; NRIP1; MXI1; MSX1; CITED2; ZKSCAN1; SATB2; HMGB2; SSX1; HOXB7; EGR3; THAP11; KDM5D; HMG20B
Down-regulation 69 JUP; TFDP2; PBX3; KMT2A; PKNOX1; BAZ2B; MED17; INSR; TLE4; HLX; ATF5; TCF4; VDR; CREBZF; MYRF; RYBP; TWIST1; ST18; HOXC4; ERG; FOXN3; TCF7L1; WWC1; NCOA2; ZNF165; HOXD1; POU2AF1; TGIF2; CTBP2; KAT6B; PNRC1; ZBED2; BNC2; PHIP; NANOG; TFAP2C; BTG1; TXNIP; KLF5; ZNF423; RBPMS; ISL1; ZNF117; LOXL2; ZFPM2; ERBB4; CBFA2T3; PEG3; HMGB3; ZHX2; DACH1; ARNT2; ZEB1; ZBTB38; RBPJ; IRF7; INSM1; CREB1; KLF9; MAF; AEBP1; ZNF331; EHF; MEIS1; HOXC6; TOX3; WT1; NFATC4; IKZF1