Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11859 Azd-5438 GSE70138 HME1 Human 3h 1.11uM EID0016
Types Number Response transcription factors
Up-regulation 193 SOX3; WDR77; CBX7; NFE2L2; NR0B2; PBX3; C1QBP; NR5A2; ERBB4; NR1H2; SOX2; APBB1; HOXA3; ZKSCAN4; TCEA2; E2F4; SCAI; MYCL; KDM4C; MED14; HDAC4; TBX10; SUPT3H; CAMTA1; TSHZ2; MYBL1; EHMT2; SALL2; SOHLH2; HOXB5; HSF4; BHLHE40; ZNF671; TP73; HOXD13; KAT2B; ZNF235; PIAS4; LHX1; BCL11A; ZSCAN16; SOX12; TCF15; ZNF154; RFX1; IRF6; MED25; MAK; CARF; TTF2; MLLT10; RAX; ZNF444; TRIB3; SRCAP; HOXA6; SOX17; ZNF623; ATOH1; ZNF500; CREBZF; ZNF682; NFE2L3; CERS6; ZNF711; ESR1; ZBED2; ZNF75D; ZNF667; HSF1; MECP2; MEF2C; ZXDC; ZNF91; FOS; ZNF688; ZNF224; THAP7; SOX18; HDAC9; CUX2; BARX1; HEY2; E2F5; FEZF2; PRDM14; HHEX; NEUROG2; TDRD3; COPS5; DLX5; HOXD3; TFAP2A; REL; ZNF573; TCEA1; ZNF165; BRWD1; ZNF467; ST18; TRPS1; ZNF654; HNF4G; TOX3; SPI1; PRDM10; EP300; PRDM12; TCF21; GFI1B; KLF11; GATA1; DACH1; NFE2; L3MBTL1; ZNF536; NKX2-1; CCNH; SOX13; ARNT2; HOXB2; NR4A2; PSMC3; ZNF589; TAL1; PMS1; SSBP3; WWP1; MEIS2; RORC; PKNOX2; ZNF232; ZNF586; PNRC1; CNBP; MBD4; TERF1; PRDM2; BACH2; RAD21; TLE2; ZNF692; ZFPM2; SUPT4H1; ZSCAN18; CBFA2T3; VPS72; NFATC4; ZHX2; ID4; FOXA2; HOXB6; AEBP1; EMX2; ZNF544; HOXD1; ZNF652; ZNF239; NCOA2; HIRA; PHIP; ELF3; INSM1; PBX1; MNAT1; NPAS2; MEIS1; MECOM; HMGA1; LIN28A; ZNF331; PRRX1; ZKSCAN1; MXI1; SOX11; WT1; IRF8; ZNF423; TFAP2C; LMCD1; LEF1; FOSB; GATA2; PAX6; ATF3; SATB2; PEG3; NKX2-2; MYB; MNDA; THAP11; NFATC3; E2F2
Down-regulation 117 ADRB2; FHL2; CCNA2; SOX4; RBM14; ZMIZ1; TBPL1; SMAD3; PUF60; GABPB1; SUV39H1; NUP62; EED; MYC; ING3; NCOA4; BAZ1B; CHD1; ZBTB38; MED1; CDK7; ZNF443; RELB; EZH2; STAT5B; NKX3-1; SNIP1; TSC22D3; TRIM32; XBP1; NRBF2; ATF1; SNW1; NFKB1; ADNP; BLM; ABL1; SMARCE1; NR1D2; BRD8; BMI1; ZNF468; KAT5; NFIL3; TLE4; DEK; RNF6; MNT; FOSL2; HMGB1; TFAM; ZFP64; ZNF266; CREB3L1; ZNF267; ZNF410; FOXJ3; KAT7; ZBTB43; E2F3; REST; STAT5A; MAGED1; FOXO1; GATAD2A; CRY1; HMGN3; ZNF432; POLR2A; PCGF2; BCLAF1; CBFB; SIX2; HSF2; RBPMS; NFAT5; ING2; RNF4; COPS2; KDM2A; ZBTB1; SFPQ; NRIP1; ELK3; KLF9; BCL10; HOXC6; SMAD7; NCOR2; ARID4B; RCOR1; JUNB; ZMYM2; APEX1; FOXD1; BRD3; JARID2; PHF20; HLTF; BBX; DNAJC2; BCL3; FOXC1; ZNF22; KDM5D; MTF2; SMARCA2; KLF2; RXRA; ELF1; RBPJ; TXNIP; TRIM29; ZBTB18; MAFB; TRIM22; HEY1