Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11837 Canertinib GSE70138 HME1 Human 3h 0.12uM EID0016
Types Number Response transcription factors
Up-regulation 40 CARM1; TAF9B; TSC22D3; ID2; CBX4; ARID5B; THRA; FOXM1; BRD7; SMARCE1; SSX1; RUNX3; RREB1; ZFPM2; CRYM; BRD8; NFIL3; BHLHE41; TERF1; HOXC6; HOXC4; HMGN3; TRIB3; SOX13; ZBTB16; TCF7L1; PIR; AFF1; HOXD1; HTATIP2; ZNF165; INSM1; TBX3; PAX6; TFAP2C; EHF; HOXC10; TRIM29; ARNT2; THAP11
Down-regulation 56 TLE1; JUN; FOSL1; MYC; ZMIZ1; FOXO3; ZNF148; BCL6; ZNF91; CUX1; HMGA2; RUNX1; BBX; RUVBL2; ZNF516; EGR3; BACH1; BAZ1A; CCNE1; NR1D2; MAFF; KLF10; KLF2; ZNF512B; ZNF83; MED1; BRD2; NRIP1; ZNF264; SIAH2; STAT6; ZEB2; SCAND1; ETV5; HEY1; ZNF652; MAGED1; RXRA; SOX11; NKX2-1; BCL3; ZNF331; BCL11B; KLF6; ESR1; LEF1; BCL11A; CREB1; MNDA; HOXB2; EGR1; EMX2; PEG3; TBX2; IKZF1; TCFL5