Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11834	Canertinib	GSE70138	HME1	Human	3h	3.33uM	EID0016

Response Information :

Types	Number	Response transcription factors
Up-regulation	72	TSC22D3; ID2; PROX1; LIMD1; LYL1; CDX1; THAP7; NR3C2; E4F1; ZNF589; POU4F1; ID3; THRA; CEBPZ; NFIL3; SOHLH2; JAK2; MLX; HDAC11; ZNF217; ONECUT2; PITX2; SAP30; ACTL6A; HOXB9; NFE2L3; SMARCE1; KAT7; ARID3A; HDAC9; SSBP3; FLI1; ZNF552; BRD8; VDR; PSMC3; ZEB1; PSIP1; TLE4; TSC22D1; ZNF266; ASCL1; PPARGC1A; TOX; TRIB3; PRRX1; FOXG1; MYB; XBP1; SMARCA2; HMGB2; NANOG; HIRA; TAL1; SSX1; SMAD1; TOB1; CUX2; CRYM; TXNIP; BCL11A; KLF2; ZBTB16; GATA6; ZBTB18; ID1; ZNF423; TFEC; THAP11; TRIM22; BASP1; PBX1
Down-regulation	80	JUN; YBX3; FOSL1; MYC; CRK; ZNF394; MGA; ZNF329; C1QBP; CHD7; ZNF551; ABL1; ZNF91; MNT; RUNX3; ZBTB11; BCL6; CNOT2; SHOX2; IKBKAP; HMGA2; MAFF; TGFB1; KLF6; ZBED4; RLF; PBX2; URI1; CHD9; RBBP5; TSC22D2; FOSB; PITX1; PPRC1; ZNF224; L3MBTL1; BCL3; NR4A3; REL; COPS2; FLNA; ZNF43; MED13; TBL1X; FOSL2; POLR2A; AHR; NFKB1; SMARCD3; MSX1; ZNF512B; SIX2; ZNF117; SCAND1; ZFP36L1; MITF; ZNF160; CITED2; BAZ1A; YWHAB; ZNF165; SERTAD2; EGR3; TCF4; HMGN3; LITAF; JARID2; IRF7; KLF11; HOXB2; TRIP6; ERG; RBPMS; SPEN; CREB1; CTBP2; HMGB3; MNDA; ZNF331; KDM5D