Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11831	Afatinib	GSE70138	HME1	Human	3h	0.12uM	EID0016

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	IRF3; CIC; TULP3; SMAD1; CALCOCO1; NFATC3; SUPT6H; ZFHX3; TSC22D3; ZNF552; MAZ; CIR1; ARID1A; CARM1; CHAF1B; ID3; ZNF444; SSBP3; ATN1; ZNF211; PLAGL2; EZH1; HOXD9; NR3C2; CDX2; USP21; HOXD1; ID2; ACTL6A; PMF1; ZNF195; ZNF580; TCF3; KLF7; MKL2; YEATS4; PIAS3; SMARCC2; LPIN2; RERE; HOXA5; HOXD10; EPAS1; VDR; TEAD4; ERBB4; GTF3A; CALR; ZFHX4; EYA1; MEIS2; SIX2; TRIM24; KDM5D; ZBTB16; ELF3; ZNF423; BRD4; TAL1; GMNN; PSIP1; MECOM; TLE4; NFE2L3; REPIN1; ZFP36L1; SOX13; POU2AF1; CRYM; ZNF217; EYA2; TBX3; ARNT2; ZEB1; ZBTB18; TCF4; ASCL1; CREB1; LEF1
Down-regulation	71	MYC; FOSL1; PFDN5; FOXL2; WWTR1; ZEB2; BBX; HHEX; PTTG1; HIPK3; TMF1; MAFF; RBBP7; ZNF426; ATF1; FOXF1; MAF; RLF; RBL2; FLNA; MITF; ZNF14; BHLHE40; ZSCAN31; NEUROD1; DNMT3B; ZNF91; ZSCAN18; ZBED2; INSM1; SMAD2; CREB5; RNF4; EGR3; NRIP1; TFEC; PEG3; ISL1; PITX1; ZNF165; ZNF160; STAT1; OSR2; SFPQ; ZNF721; NAB1; CTNNB1; CITED2; EN1; RUNX1; NR4A2; TSC22D2; BASP1; TRPS1; PAX5; GATA6; ID4; NKX2-2; TGIF1; EGR1; KLF6; RBPMS; HMGB2; TOX3; CTBP2; ZFPM2; HOXB2; PAX6; ESR1; HOXC6; TXNIP