Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11828	Afatinib	GSE70138	HME1	Human	3h	3.33uM	EID0016

Response Information :

Types	Number	Response transcription factors
Up-regulation	74	MEF2C; HMGB1; TAF11; TSC22D3; CALCOCO1; ID2; DMTF1; VGLL4; CBX7; CENPF; ZNF500; ZMIZ2; ZNF419; POU2F1; EHMT2; FHL5; PRDM2; ARID5B; CARHSP1; TP63; GTF2F1; PBXIP1; FOXN3; KDM5D; EZH1; RORA; ZNF432; ZNF331; PAX5; FOXG1; ZNF586; SSBP2; NR5A2; ZBED1; KAT2B; JUND; NR3C2; CREM; CERS4; ZNF32; PSIP1; ZNF606; ZNF532; TCF4; HMGB2; ZIC1; MEOX2; BMI1; ESR1; MKL2; TFAP2C; ID3; LOXL2; NR2F1; SAP30; SHOX2; HOXC10; TRIB3; RXRA; ZMYND8; CITED1; ELF3; TRIM16; TWIST1; POU2AF1; LMCD1; HMGB3; MYBL1; AEBP1; MEIS1; MEIS2; ZNF423; THAP11; HMG20B
Down-regulation	48	SMAD3; MYC; FOSL1; OVOL2; NFE2; HMGA2; MSX1; ARNTL2; PLAGL2; E2F6; MYCN; CHD7; RYBP; MXD4; ERBB2; BAZ2B; ZBED2; NFKB1; MBD2; MYCL; TFDP2; HOXB6; RNF111; RNF4; FOXD1; BCL10; CTR9; AGO2; IFI16; BBX; ZEB2; BAZ1A; MYB; NKX3-1; MNDA; PPARG; HOXB7; SATB2; RBPJ; WWTR1; TOX3; WT1; PEG3; ASCL1; GATA6; MAFB; HOXC6; TCFL5