Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11816 Cgp-60474 GSE70138 HME1 Human 3h 3.33uM EID0016
Types Number Response transcription factors
Up-regulation 69 LZTR1; SPDEF; SCMH1; ZNF358; GTF2I; SALL2; NOC2L; EHMT2; CDK9; ZSCAN18; ZNF665; ING4; TFAP2C; CIZ1; PFDN5; BHLHE41; AES; MYRF; PMS1; HDAC5; PHIP; EHF; ZNF611; ZNF544; PSMC3; CREB3; EMX2; RFXANK; TGFB1I1; RNF141; GTF2F1; MEIS1; RUVBL2; ZNF667; TCEB2; TCF3; CBFA2T3; EDF1; MEIS2; ZNF593; ZNF160; PSIP1; ZNF43; HOXB13; BCL11A; TAF10; ZNF91; ZNF93; NPAS2; DLX5; JUP; TLE4; ZNF711; SMARCD3; HMGN3; AEBP1; LOXL2; TRIM29; NR2F1; CITED2; SOX11; TOX; ARNT2; HTATIP2; ID4; WT1; PAX6; PBX1; SSBP2
Down-regulation 127 NFKBIA; MYC; FOSL1; ADRB2; TBP; SOX4; ABL1; RELB; SMAD7; HES1; BHLHE40; TCERG1; RELA; PLAGL2; HOXA5; KAT6A; GABPB1; CCNA2; ELF1; CEBPB; ASXL1; RORA; SUV39H1; SERTAD2; ZNF281; NFKB1; BRD2; KLF10; TOPORS; RLF; NFIL3; FOXO3; JUNB; RNF6; MAFG; ZNF267; SNAI2; ADNP; BTG1; ZBTB7A; ZMIZ1; SNIP1; MAFB; MED1; ZBTB38; NUP62; NRBF2; XBP1; PPRC1; MSX1; RNF4; ELK3; NRIP1; FOXO1; ING2; PROX1; VEZF1; SIAH2; PPARGC1A; E2F6; ZFP36L2; BRPF1; ZBTB1; CCDC59; RBM14; REST; TFAM; ARNTL; SFPQ; MSC; ZEB2; POLR2A; NCOA6; IRF2; KLF13; TSC22D2; IRF1; TAF4; HMGB1; YWHAB; MEOX2; MBD2; NFAT5; CBFB; ETS2; MED13; BACH1; SF1; KLF6; KLF4; BCL10; AHR; EGR3; SAP30; BCL3; ZFP36L1; ZMYM2; FOXJ3; NKX3-1; JARID2; RUNX3; NKX2-1; PITX1; BRD4; FOXD1; NR3C1; FOSL2; ZBED1; ENO1; TAF1D; MKL2; RBPJ; MYBL1; KLF2; BASP1; FLNA; HMGB2; RXRA; TGFB1; SATB2; EGR2; SOX9; HHEX; ASCL1; KDM5D; SMAD1; TOX3