Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11804 Pf-562271 GSE70138 HME1 Human 3h 10uM EID0016
Types Number Response transcription factors
Up-regulation 217 DLX6; LZTR1; PAX9; NR5A2; SIM1; POU1F1; SMAD6; VGLL1; ZBTB18; TTF2; FOXA2; ACTL6A; ZNF407; ING4; DLX5; ZNF257; ZNF254; TOX3; NEUROD1; ZNF674; NEUROG2; CARF; TGFB1I1; SOX3; MSX2; ZNF80; FOXD2; THRB; HNF4G; PITX3; INSM1; MDFI; ZNF214; ZNF41; ZIC3; MED14; SCAI; BRCA2; PAX4; THAP9; ZNF81; GSC2; SHOX; SRY; ZNF33B; TLX1; POU6F2; ZNF157; GCM2; ASCL2; SND1; HOXA3; ZNF225; ZNF682; NFE2L3; MZF1; PRDM9; ONECUT1; HES2; ZNF208; ZNF391; EZH1; ZNF219; FEZF2; GTF3A; ANKRD1; ZNF780B; ATOH1; FOXD3; TLX3; PRDM5; DCC; RXRG; NFE2L1; SOX18; HOXD12; VHL; EMX1; E2F2; ETV4; ZFP69B; MAML3; POU2F3; ZNF667; ZBTB44; ZNF471; ZNF749; POU3F3; TFEC; ZNF507; ZNF711; TBX1; STAT2; ZNF695; MMS19; ZNF551; HSBP1; ZNF580; HDGF; NR5A1; SALL2; HDAC5; EHMT2; SIX3; PEX2; NR1H4; MITF; KAT2B; MYCL; NR1I2; PAWR; CDX2; ONECUT2; EPAS1; TUB; NKX2-1; CTBP2; ZNF141; MNAT1; TOX; PITX2; THRA; BCL11A; POU4F2; SMARCC2; CSDC2; AFF2; NHLH2; LIN28A; MYF6; HIF3A; RAD21; HDAC9; ZNF532; PRDM12; BAZ2B; FOXE1; ZNF215; SSBP3; PGR; MYCN; SP140; POU5F1B; KAT8; ZNF516; MYT1; ZNF112; LYL1; TBL1XR1; CNBP; ZSCAN18; SPIB; CBFA2T3; PSIP1; TULP3; ZNF117; EN1; ZNF350; BRCA1; ZNF415; ELF3; PRRX1; MBD4; E2F5; ID4; PLAGL1; PBXIP1; CERS4; ARNT2; ID1; TCF7L1; ZNF32; ZBTB20; CREBL2; FUBP1; NANOG; VPS72; TCF7L2; EYA1; TLE2; CREB3L1; TRIB3; ERBB4; EHF; SMARCA2; ST18; HOXB5; E2F8; TCF21; SMARCA1; PBX3; REPIN1; GRHL2; MXI1; NR1H3; HOXB6; HMGN3; PAX5; ZNF91; JUP; MYBL1; NR2F2; TWIST1; TRPS1; NFIB; MEIS2; HMGA1; TXNIP; SOX11; HOXB2; PBX1; ASCL1; DACH1; EMX2; TRIM22; BASP1; NFATC4
Down-regulation 144 FHL2; NFKBIA; MYC; FOSL1; RELB; SNAI2; TBP; JUN; SNIP1; NFKB1; HES1; ASXL1; CCNA2; CEBPB; SFMBT1; BHLHE40; GABPB1; HOXA5; KDM2A; EGR3; SOX4; IRF1; SERTAD2; PLAGL2; JUNB; TAF9; CRY1; NKX3-1; XBP1; FOXO1; NUP62; NFIL3; ZBTB7A; ZBTB43; RBL2; RELA; MNT; SUV39H1; ZNF200; ING2; CCDC59; ZBTB1; MAFF; CNOT2; MEF2A; MED17; BCL10; ZBTB11; SMAD3; GMEB2; NRIP1; RORA; KLF9; TSC22D2; CCNE1; ZNF267; SIAH2; EGR2; HMGB2; E2F3; RRN3; ZMIZ1; CENPF; MAFB; USP22; DDIT3; UBE3A; RNF4; ERF; ELF1; ARID4B; RUNX1; ETS2; RLF; TAF11; RREB1; FOSL2; PHF20; IRF7; RNF138; MED1; SMAD7; BRD2; CHD1; KLF10; MDM2; ABL1; VEZF1; HHEX; ZNF212; NRBF2; ZNF432; BAZ1A; BRD4; IFI16; TRRAP; BRPF1; KMT2A; MAF; RCOR1; E2F6; ERBB2; RYBP; REST; USP16; CTR9; TFAM; JUND; PIAS2; IKBKAP; CEBPG; BCL3; WHSC1; ZFP36L2; ZNF266; POLR2A; YWHAB; COPS2; PRKDC; JARID2; ELK3; PTTG1; ZFP36L1; HLTF; VDR; KAT6B; FOSB; SFPQ; KLF6; TGIF1; SAP30; FOXC1; HOXC6; AFF1; KLF2; TBX3; SMAD1; FLNA; HOXC10; HMGB3; KDM5D; SOX9; ETS1; IKZF1