Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11797 Palbociclib GSE70138 HME1 Human 3h 0.04uM EID0016
Types Number Response transcription factors
Up-regulation 48 NCOR1; SP2; FOS; EWSR1; MED14; NR4A2; FOSL2; SMAD7; PRPF6; HMBOX1; BCLAF1; MNAT1; VDR; ESRRG; ERBB4; TCEA1; ZFHX3; NR4A3; HOXA5; EPAS1; JUP; ZNF532; SMARCC2; BACH2; MEIS1; RCOR1; RBFOX2; CREM; VPS72; ARNT2; FOXJ3; TRIB3; SOX17; FOSB; ZNF423; ID3; HOXB7; HTATIP2; DACH1; TOX; TOB1; NKX2-2; TBX3; HOXC10; THAP11; NR2F6; ID1; HOXC6
Down-regulation 38 ZNF148; CRK; RBBP5; ZNF91; CBX6; DEAF1; NR1D2; TBL1X; ZMIZ1; ZNF665; TAF10; CITED1; CTR9; NRIP1; HLF; ZKSCAN1; MXI1; HLTF; PITX1; CTNNB1; BBX; SCAND1; TFAP2C; ETV5; TRIP6; BNC2; SPEN; MYB; NR2F2; INSR; NKX3-1; KLF9; MNDA; ZBTB18; SMAD1; EGR3; GATA6; IKZF1