Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11772 Saracatinib GSE70138 HME1 Human 3h 0.12uM EID0016
Types Number Response transcription factors
Up-regulation 14 SOHLH2; PITX1; PURA; WWTR1; TSC22D3; NFIL3; NANOG; ZNF83; THAP11; PEG3; ID3; ZFP36L1; CITED2; PAX6
Down-regulation 41 PUF60; CRK; MED6; ZNF430; ZNF160; GATA3; SIX2; SERTAD2; ZEB2; NR3C2; ZNF91; NAB1; CHD7; SIX3; MED13; ZKSCAN1; SP3; IRX5; MYCL; TCF7; RYBP; JUNB; HMGN3; BAZ1A; SFPQ; NRIP1; NFIB; BCL3; PLAGL1; KDM5D; ZNF721; HIPK1; PBX3; CREG1; BHLHE41; SOX11; MYB; CREB1; DACH1; IKZF1; TCFL5