Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11761 Fostamatinib GSE70138 HME1 Human 3h 0.04uM EID0016
Types Number Response transcription factors
Up-regulation 49 GATA3; POU2F2; GATA2; YEATS4; PURA; BCLAF1; ITGB3BP; ZNF536; RAD21; CHD7; NFATC3; HOXB5; MYT1L; IKZF1; ATF7IP; EYA1; ACTL6A; IRF4; MSX1; HOXA5; YWHAB; PAX5; SOX10; HOXB6; JUNB; ZBTB38; TOB1; AGO2; PHOX2B; TBX3; CREM; HDAC9; TRPS1; PEG3; HOXB7; ISL1; BTG1; RUNX3; SMAD7; ASCL1; WWTR1; ERG; LITAF; GATA6; HOXC6; TOX3; THAP11; CREB1; TXNIP
Down-regulation 59 NSD1; BCL6; ERF; ST18; RREB1; GTF2IRD1; ATN1; NFYC; PITX2; TRIM24; HLX; ZNF544; CDIP1; NR4A3; TEAD4; HMGB3; FOXE1; IRF7; ZSCAN31; ZNF239; FOXG1; ID4; BNC2; HMGN3; NR5A2; NR4A2; NR4A1; NFATC1; ZBED1; FOSL2; ELF3; YAP1; PLAGL1; KLF11; ZNF165; SOX13; HHEX; TFAP2C; PITX1; SCAND1; NKX2-1; IRF8; CBFA2T3; MNDA; CRYM; ZFPM2; CITED2; SOX17; RBBP8; KLF4; TGIF1; MAFB; HIRA; FLNA; AFF1; ZNF91; SOX11; EGR2; KDM5D