Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11759 Fostamatinib GSE70138 HME1 Human 3h 0.37uM EID0016
Types Number Response transcription factors
Up-regulation 48 CITED2; NR4A2; SUMO1; MNT; TBL1XR1; CHD9; FOS; NPAT; TGIF1; HOXA5; TSC22D3; LYL1; CBX5; KLF1; FOSB; ZNF430; ZBTB1; NR4A1; PHIP; CNBP; ZNF195; ARNTL; AHR; CRYM; ZBED2; ZNF331; BAZ1A; TFAP2C; NKX2-1; SMARCA2; IRX5; CREB1; FOXG1; KLF10; SOX9; NRIP1; EHF; EGR2; RBPMS; KLF6; HMGB3; PAX6; ZFP36L1; ID1; TRIM22; ATF3; THAP11; HOXC6
Down-regulation 41 PUF60; TLE1; SUZ12; ADRB2; TAF5; RELB; NKX3-1; PIR; PLAG1; MBD2; MSX1; PKNOX2; NFKB2; CRY1; NFKB1; ZNF24; CHD7; SOX17; BCL6; HEY2; HDAC9; NCOA6; NR2F2; SAP18; ZEB2; IRF1; OSR2; HHEX; ISL1; ZNF652; MYCN; MECOM; SCAND1; ZBTB18; SPEN; ST18; PBX3; TOX; HEY1; GATA6; DACH1