Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11752 Gsk-1059615 GSE70138 HME1 Human 3h 3.33uM EID0016
Types Number Response transcription factors
Up-regulation 49 GATA3; TSC22D3; ELF5; NFKBIA; ID2; ARID5B; PSPC1; NCOA2; HES1; ZMIZ2; YEATS2; BRD8; PMS1; CEBPD; TRPS1; ESR1; ATF4; HTATIP2; PHF20; TBL1X; HBP1; ING3; RBBP8; JUP; RORA; IRF1; PLAGL1; NFIL3; PHIP; PSIP1; ZNF302; ZNF83; CITED2; HOXD1; TLE4; IRX5; TOB1; KLF5; KAT6B; MYB; TRIM29; MAFB; ERBB4; RFX5; CREB1; BASP1; ATF3; PEG3; HOXC6
Down-regulation 54 FOSL1; SNAI1; THRAP3; ECD; AFF4; GATAD2A; TAF9; CHD7; BHLHE40; PTRF; SMARCA5; CTNNB1; MAFF; STAT3; ZMIZ1; MDM4; GTF2I; HIPK3; NFIC; TGFB1; EPAS1; ETS1; BATF; HMGA2; BCL10; FOXF1; NR4A3; KLF9; PRRX1; CBFB; RBBP4; SOX9; EGR3; FOXF2; FLNA; FOSL2; NR2F1; LOXL2; MYRF; HHEX; CITED1; ETV5; NKX3-1; KLF10; HEY1; ID4; GATA6; INSM1; HOXB6; SATB2; NR2F6; AEBP1; LEF1; EGR2