Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11729 Alvocidib GSE70138 HME1 Human 3h 3.33uM EID0016
Types Number Response transcription factors
Up-regulation 23 RELB; GATA2; PRKDC; PEX2; FOS; SREBF1; ACTL6A; HMGB1; SOHLH2; TAL1; ENY2; ZNF224; NFIL3; ID3; NFE2L3; STAT3; ZNF532; MECOM; ZNF91; CREB1; LOXL2; LEF1; ID1
Down-regulation 126 NFKBIA; MYC; FOSL1; ADRB2; JUN; FHL2; SOX4; BHLHE40; ZNF394; KAT6A; BRPF1; MAFF; ETS2; ZFP36L2; TSC22D2; HOXA1; MED17; KLF10; IRF1; SERTAD2; SNIP1; ABL1; BAZ1B; KLF6; HES1; TBPL1; CDK7; NRIP1; TSC22D3; ARID4B; ADNP; JUNB; SMAD3; SUV39H1; XBP1; MAFG; ZEB2; ARID5B; FOSL2; CHD1; BLM; BCL10; POLR3F; RLF; ZNF443; BCOR; CAMTA1; CHD8; KLF9; PPRC1; ZNF426; ATF3; ZMIZ1; KLF4; ZBTB24; TGIF1; ZNF267; HSF2; E2F6; JUND; VEZF1; ZNF189; BIRC2; HHEX; MED23; ELF4; NKX3-1; DAXX; SMAD7; ZNF430; PPARD; HOXA5; BACH1; ZBTB43; ZNF12; ELK3; NRBF2; EGR3; PLAGL2; GATA6; CITED2; MED24; AHR; SIX2; KLF2; HIC2; DDIT3; FOXJ3; CEBPB; ZNF281; RNF138; BTG1; NR4A1; PITX1; THAP10; IRX5; ZNF264; DLX2; MEOX2; TERF2; FOSB; BAZ1A; MAFB; FOXC1; SALL1; ZBTB18; CITED1; ZNF107; TOB1; PAX5; ATF4; SCAND1; ELF3; LMCD1; TBX3; WWTR1; TSC22D1; BHLHE41; MYRF; NR3C1; SOX17; EGR2; SOX9; BASP1; THAP11; HOXC6