Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11707	Mitoxantrone	GSE70138	HME1	Human	24h	0.37uM	EID0015

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	SOX4; ATF3; TOB1; ATF5; TFAP2A; RFX5; IRF1; MYBL2; FOXO4; HDAC9; CEBPZ; STAT1; PSMC3IP; MAF; BHLHE41; TP53; ARID5B; ZNF593; ZNF302; HDAC5; PCGF3; ZNF266; PNRC1; E2F3; TOX; BRCA1; RBBP8; PBX1; ZBED2; NR1D2; ZNF432; ZNF331; ZNF665; FOSL2; FOXO1; DLX2; BCL3; NR4A1; PHF1; KLF11; FOXF2; RUNX1; IRF7; ADRB2; TWIST1; NAB1; TRIM29; ID3; ZNF232; VPS72; JUND; ZNF544; HOXA5; EGR2; DACH1; DLX5; INSR; ID4; TXNIP; ZFPM2; PEG3; MYCL; ZBTB38; ID2; KLF5; OSR2; PBX3; ESR1; AEBP1; ID1
Down-regulation	49	ECD; PCBD1; HMGA2; XBP1; NR3C1; MMS19; ENO1; GABPB1; CBFB; CENPF; BRD7; NFKB1; SPEN; PIAS1; PRMT2; ARRB1; IRX5; TBL1XR1; JARID2; IRF2; PURA; HMGA1; CUX1; CBX5; DNMT3B; CD3D; FOXJ3; CHD9; ARID1A; HMGB2; CRYM; SUPT3H; HNRNPD; SMAD1; PPARG; HIRA; ZMIZ1; BASP1; TGFB1; HOXC6; FLNA; CREB3L2; CCNA2; THAP11; ELK3; SAP30; ZBTB16; NR2F2; IKZF1