Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11703 Chir-99021 GSE70138 HME1 Human 24h 0.04uM EID0015
Types Number Response transcription factors
Up-regulation 35 PHOX2B; KDM5A; KLF7; NFX1; PHOX2A; TBX2; IRX5; HAND1; ELF4; SCAND1; ZNF124; CEBPZ; LDB1; GATA3; MECOM; HEY1; PLAGL1; RBPMS; EN1; HOXC10; CEBPD; CREB3L2; RBBP8; SMAD6; FOXF1; PITX1; NR2F2; TXNIP; BTG1; CALR; OSR2; TRPS1; ELK3; ZIC1; LEF1
Down-regulation 37 TAF9; ETV1; NR3C2; FOXO1; ZNF146; HMG20B; ADNP; RNF6; ZBTB1; NKX2-2; NFYB; NR4A3; RNF138; NRIP1; SOX10; TGIF1; HLF; NR4A2; TSC22D2; FOSL2; CRYM; MNDA; NKX3-1; EGR2; RUNX3; TRIM16; BHLHE41; MYB; ZEB2; EHF; PTTG1; GMNN; ZBTB16; TRIM22; TSC22D1; GATA6; BASP1