Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11678 Torin-1 GSE70138 HME1 Human 24h 0.12uM EID0015
Types Number Response transcription factors
Up-regulation 133 SOX4; HBP1; MYC; KDM5A; EZH1; SP100; NFAT5; MNT; ATF4; KLF7; ZNF415; IRF7; SKI; TFAP2A; ZNF266; EP300; ZNF91; ZNF669; ZNF83; ZNF665; FOXO1; ZNF573; TGFB1I1; SETDB1; ZNF345; BACH2; CALCOCO1; PNRC1; CUX1; TSG101; HMGA2; BRD4; MXI1; HMBOX1; ZNF264; SP110; ZNF141; BPTF; ZNF160; PLAG1; IKZF1; PPP1R13L; RSF1; CBX7; ZNF148; ELF4; VPS72; ZNF532; PHF20; ZBED2; SMARCD3; MED13; NCOA3; IRF9; BACH1; TGIF2; ZNF721; BNC1; HIVEP1; TFEB; CSDE1; SUPT3H; ZNF93; ZNF217; ZNF500; INSR; CERS6; TAL1; FOXN3; NR2C1; KLF13; ZNF239; MYRF; ZNF587; MNDA; WT1; MAFF; HOXD1; PEG3; KLF9; ZNF117; ZFPM2; NPAS2; TRIM29; NFE2; ZNF3; TCF7L2; TRPS1; TRIM22; LDB1; ZMYM2; KAT6B; ZNF589; STAT4; NFIC; RXRA; ZMIZ1; HLF; KLF10; ZSCAN18; IRF4; TLE4; HDAC9; BIRC2; BHLHE41; TBL1X; PLAGL1; TWIST1; MEOX1; NFIB; ZFP36L1; IRF1; BCL11A; ZNF544; LMCD1; TLE1; SOX11; TXNIP; MAFB; BBX; ZKSCAN1; ELK3; LITAF; PDLIM1; ZHX2; ZBTB38; NR1D2; JUP; TCF4; MAF; GATA6; ARNT2; SOX9
Down-regulation 61 EZH2; MYCBP; TFDP1; GTF2A2; FOXM1; MYBL2; CDK2; NEDD8; RFX5; CCNA2; SSRP1; PARP1; MAZ; PHF8; UBP1; HMGB2; KAT7; C1QBP; IRX5; BRD7; RBM14; HOXC6; MED21; TRIM28; CBFB; E2F8; SIAH2; CENPF; YWHAB; CD3D; MSX1; THAP11; RNF4; PTTG1; BATF3; BCLAF1; GABPB1; CARHSP1; NR0B1; HIPK1; CBX5; HSBP1; PIR; CHD9; ENO1; CITED1; FOXF1; JUN; ARID1A; DNMT3B; HOXC10; SUB1; SAP30; JUND; NANOG; HTATIP2; TRIM16; ELF3; HOXB7; SUV39H1; ASCL1