Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11646 Azd-7762 GSE70138 HME1 Human 24h 10uM EID0015
Types Number Response transcription factors
Up-regulation 341 NFKBIA; SOX4; FOXO4; TSC22D3; HBP1; NFIL3; CALCOCO1; PNRC1; HDAC5; EZH1; CBX7; ZNF76; TFAP2A; HINFP; CEBPD; MXI1; CARF; RELB; COPS2; PHF1; SOHLH2; MZF1; ZNF768; ZNF665; ZNF286A; BCL3; ZBTB40; RXRB; ZNF83; ZNF711; ARID5B; HESX1; PRDM2; TSHZ2; SETDB1; RSF1; ATF4; BCL11A; ZMYM2; ZNF117; BCL6; NFRKB; ELF4; IRF1; HIVEP2; ZNF331; ALX3; FOXN3; ASCL3; HABP4; RING1; NCOA2; EHMT2; RBM39; CIR1; ZNF688; ZNF510; NFE2L2; TAF1C; CBFA2T2; KLF9; CSDC2; MED12; ARID5A; ZNF74; STAT2; ZNF44; POU5F1B; SMAD6; SIRT2; ZKSCAN4; ZNF91; PBX1; SMARCD2; MEF2C; ZNF154; INSR; KLF11; CIC; FOXO3; ZNF345; ZNF177; ZNF43; TBX4; MAML1; PRDM14; ZNF667; ZNF266; ZNF611; TCEA2; HDAC9; CBFA2T3; ZNF337; L3MBTL1; GCM1; DBP; AIP; KAT2A; MLXIPL; ZMIZ1; ZNF500; ARID3B; BPTF; ZNF506; ZNF358; LZTR1; CRTC1; JUND; ZNF85; TRPS1; BRD4; MDFI; ZXDC; RYBP; UBE2B; SUPT5H; CREG1; ZKSCAN8; ZNF224; NONO; PCGF3; DYRK1B; TAL1; BRD2; FOXH1; TSG101; ZNF415; PKNOX2; PIAS1; ZNF253; SRF; NR2C1; ZNF133; GLI3; ZNF33B; ZFHX2; TEAD3; NFATC4; ZSCAN18; NAB2; PEG3; ZIM2; ZNF675; DDX17; MEF2A; RORA; MYCN; ZNF135; HMBOX1; TAF11; ZNF589; SIM1; STAT5A; SP100; CHD2; SUPT3H; VPS72; FUBP1; ZNF141; HOXA4; ZNF419; HDAC7; RCOR3; NHLH1; CIITA; ZIC3; KMT2A; OSR2; ING4; LIN28A; ZNF24; KLF3; ASXL1; KAT6B; MNDA; PITX3; HIF3A; TCF25; ZNF334; MEIS2; LYL1; ZSCAN31; TBX1; IRF7; ZNF75D; CDIP1; ZNF573; ID4; HNF4G; SRY; SND1; SP110; ZNF211; TGIF2; NFAT5; GATA1; NR4A2; ZHX2; KDM5C; NFKB2; NR1H3; PBXIP1; DDIT3; GFI1; ZNF646; APBB1; ARID3A; YEATS2; BNC2; SUPT4H1; EMX2; CREBL2; KLF7; ZFPM2; CRX; CSDE1; FOXO1; THRB; ZNF112; ZBTB20; ZNF160; MAF; MECP2; PLAGL1; EPAS1; ZNF93; SOX12; NFIX; ATF3; ZNF444; PFDN5; ZNF273; EN1; TBX3; ZNF264; HR; PPP1R13L; NFE2; ZNF606; MEF2D; ZNF682; ZNF350; ZNF423; ZNF580; ZNF219; KAT2B; TRIM24; BRD8; CBX3; ZSCAN9; TOX; STAT5B; ZNF529; MYOG; PIAS4; CNBP; WNT4; NCOA3; PLAG1; ZNF467; NR4A3; LDB1; ZNF205; ZMIZ2; ARHGAP35; TRAK1; SETD2; JUP; WT1; NR0B2; NANOG; PAXBP1; PHIP; ATN1; EVX1; KLF1; RXRA; TLE4; RBPMS; HOXB1; ZNF671; NFATC1; ZNF302; MYRF; SOX13; FOXF2; NCOA1; SSBP3; MEIS1; CDYL; ESRRG; BANP; CITED2; TCF15; HOXD3; ZNF430; FLI1; VGLL4; ST18; TCF7L2; JAK2; TCF7L1; IRF9; SALL2; CUX2; IRF6; BTG1; ERBB4; TFDP2; GTF3A; KLF5; HLX; RBPJ; HOXA5; TCF21; HLF; BACH2; GATA6; NR1D2; PDLIM1; ZMYND8; TDP2; ELF3; VDR; ZKSCAN1; BARX1; TRIB3; SATB1; DACH1; KDM5B; TSC22D1; THAP11; ZEB1; TXNIP; POU2AF1; TWIST1; ID3; ARNT2; SSBP2; ESR1; NFATC3
Down-regulation 90 FOSL1; MYCBP; CDK2; TFDP1; EZH2; RUVBL1; CBFB; HMGA2; FHL2; TCERG1; NEDD8; BRCA1; C1QBP; GTF2A2; PRKDC; YWHAB; TRIM32; EGR1; ETV1; GABPB1; XBP1; RBM14; ZNF672; URI1; FOXM1; DRAP1; ELK3; PARP1; DNMT1; TSC22D2; CCNA2; PSMC3IP; CLOCK; SFPQ; PREB; WDR77; ARNTL2; RBBP4; RUVBL2; CRY1; BRD7; ENO1; BCLAF1; LOXL2; EGR3; CENPF; ATF5; ADRB2; PSMC3; MAGED1; RNF4; TAF1D; CCNC; RAN; HOXB7; IRX5; CHD7; TOPORS; WWTR1; HNRNPD; SUB1; ITGB3BP; CTNNB1; SLC2A4RG; MSX1; HOXC6; BAZ1A; ZBTB18; ILF2; NKX3-1; NR2F2; BHLHE40; JUN; ETS2; NKX2-1; HSBP1; MED1; BCL11B; MYBL1; SOX9; SATB2; HMGA1; PUF60; TRIP6; SUV39H1; FLNA; HLTF; SMAD1; PTTG1; LEF1