Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11617 Gsk-1904529a GSE70138 HME1 Human 24h 10uM EID0015
Types Number Response transcription factors
Up-regulation 73 CEBPA; NR3C1; HDAC9; MEF2C; ZNF536; NFKB2; KLF7; NR1H4; POU2AF1; BARX2; BCL11A; IRF8; HAND1; PFDN5; HHEX; SHOX2; ZFPM2; JUN; IRF6; FOXJ2; KLF4; HOXB5; FOXF1; FLI1; NAB2; FOXF2; TFEB; CEBPZ; GFI1; ZNF606; E2F2; ZSCAN31; PBX1; WNT4; PLAGL1; IRX4; TCF4; NR0B2; IRF9; ZBED2; HEY2; HOXB2; SMARCD3; INSR; ZFHX4; CTBP2; MNDA; TRIM22; KLF6; TP63; CBFA2T3; HOXB6; KLF11; PAX5; SOX17; HOXB7; DACH1; BARX1; SOX11; FOSB; MEIS1; RBPJ; JUP; TLE4; TFAP2C; ESR1; ARNT2; HMG20B; ZBTB38; KDM5D; CREB1; PEG3; WT1
Down-regulation 43 NFIL3; ETV1; CRY1; THAP11; UBP1; BCL11B; KAT8; ZMIZ1; TFAM; MKL2; ENO1; PSIP1; ZNF331; KLF9; ATF1; LPIN2; GTF3A; JUNB; LITAF; NR1H3; MEF2A; DEK; SIX1; NFAT5; CBX3; MED21; DMTF1; SIX2; NUP62; BLM; FOXO1; TGIF1; NKX3-1; NR4A2; NRIP1; ZNF652; ZKSCAN1; LEF1; NR1D2; CALR; TSC22D1; SSBP2; TCFL5