Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11615 Bms-387032 GSE70138 HME1 Human 24h 0.12uM EID0015
Types Number Response transcription factors
Up-regulation 127 PPARD; GATAD2A; PPARA; GMEB2; MXI1; ETS1; TFAP2A; ZNF419; ZNF557; KLF4; RARA; ELF4; IKZF5; SUV39H1; KLF3; ZBTB43; ZNF787; REPIN1; ZNF473; ZNF211; EGR1; PPP1R13L; IRF6; OLIG2; LHX2; TAF11; TSC22D3; ZNF253; ZNF14; TOB1; ZNF410; LYL1; HNF4G; NR3C2; PPRC1; ZNF274; DACH1; PTRF; BIRC2; LHX6; BRD4; ZNF7; ZNF444; ZNF304; SOX21; KAT2A; SNW1; CDX1; KLF7; ZNF83; KLF9; HSF1; SRY; ZNF273; RNF138; BRD2; CBX2; PRDM2; TDP2; LHX3; ZNF426; OVOL2; ATOH1; FUBP1; UBTF; CEBPD; ARNTL; TXNIP; ZNF136; ZNF667; PIAS2; ZNF587; TFCP2L1; MXD1; SAP18; NEUROD1; EHF; ZFP36L2; SP100; FOXJ3; PAX6; DMTF1; E2F2; IRF8; EN1; ZNF264; ARID5B; ZNF430; NCOA4; BCL11A; EPAS1; AR; TFEC; VPS72; ATF3; NFATC4; KLF13; FOXF2; ESR1; HDAC9; CUX2; SOX17; CBFA2T3; INSR; FOSB; SIX3; ZKSCAN1; SATB2; OSR2; HTATIP2; ZNF91; VGLL4; MECOM; INSM1; PAX5; TRPS1; BTG1; PITX1; ASCL1; ZIC1; IRF9; TCF21; SOX9; ARNT2; MYB; GATA6; PEG3
Down-regulation 61 HDAC6; IKBKAP; ETV1; NEDD8; ECD; EZH2; GTF2A2; PSIP1; HMG20B; CBFB; CBX5; CENPF; PRKDC; MAZ; LOXL2; ACTL6A; CBX3; XRCC6; CCNA2; HOXB7; CNOT6; FOXD1; TBL1X; IRF4; APEX1; MAGED1; TCF12; BRCA1; SREBF1; RBBP4; HMGB1; LPIN2; HOXD11; ATF4; NFE2L3; CHD9; DNMT3B; SMARCA1; BCL11B; SIX2; ID3; ZMYND8; TAF10; IFI16; HOXB2; JARID2; SMARCA2; PBX1; ELF3; MEOX2; MEIS2; HOXC6; RBPMS; SUB1; ID2; TRIP6; ZBTB16; ELK3; KLF2; WT1; ID1