Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11608	Canertinib	GSE70138	HME1	Human	24h	3.33uM	EID0015

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	TP53; NFKBIA; MXI1; CREG1; HOXA7; EGR1; CEBPD; NFIL3; PCGF2; CALCOCO1; TFAP2A; TSC22D3; HOXA10; FOXO4; HBP1; HOXB9; SND1; MZF1; TOX; BTF3; HOXA11; ZNF358; NR1I2; NCOA2; ATF3; CNBP; RXRA; AIP; CDX1; DACH1; DDX17; KAT5; ZIC1; PBXIP1; BTG1; CERS6; SETDB1; ATF4; DDIT3; HOXA5; DBP; SMAD6; PNRC1; ZMIZ1; MEIS1; NR4A1; ZNF91; BAZ2B; DMTF1; SALL1; UBE2B; JUND; PPARGC1A; GTF2IRD1; EYA1; MED1; SIX1; CRYM; HTATIP2; IRF7; FOXN3; CREBL2; ERBB2; IRF9; TDP2; SATB2; BRD4; JUNB; LITAF; INSM1; FOSL2; PAX6; TRIB3; HLF; PLAGL1; EYA2; MAFB; WT1; KAT6B; OSR2; ETS2; TRIM16; VPS72; TLE1; ID3; AHR; EMX2; ERBB4; MEIS2; SSBP2
Down-regulation	54	FOSL1; MYCBP; UBP1; FOXM1; ARNTL2; EZH2; C1QBP; CBFB; ETV1; CRY1; WHSC1; DR1; ARL2BP; MAGED1; ILF2; URI1; WDHD1; BAZ1A; MYBL1; RAN; RCOR1; FOXK2; WWTR1; BCLAF1; CCNA2; HMGA2; HDAC1; CENPF; SFPQ; THAP11; HNRNPD; PRRX1; ELK3; ZMYND11; HMGA1; IRF8; TGFB1; SPIB; HMGB2; HMGB3; MYB; HHEX; ZBTB18; ZNF512B; KLF2; SUB1; PEG3; ID4; HOXB2; PTTG1; TFAP2C; SUV39H1; SATB1; TOX3