Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11604 Afatinib GSE70138 HME1 Human 24h 0.37uM EID0015
Types Number Response transcription factors
Up-regulation 47 GLI2; EGR1; NFKBIA; NCOA2; TP53; CEBPD; TGFB1I1; TSC22D3; CREG1; ST18; JUND; ZSCAN31; ZNF580; TOX; FOXL2; TCF7L1; TBX1; SMARCD3; COPS5; TERF1; ID3; ATF3; TRIM16; NR1H3; BACH2; RBPMS; SHOX2; ERG; HOXB7; JUP; ELF3; ID4; EPAS1; KLF5; MYBL1; SMAD6; HDAC9; TRIM29; MEIS2; OSR2; ZEB2; FLNA; PDLIM1; MAFB; ZIC1; TLE1; AEBP1
Down-regulation 22 FOSL1; ETV1; ZMIZ1; CCDC59; RERE; HMGA2; TFAM; MYB; TCF7; KLF10; BHLHE40; CREM; BASP1; NRBF2; ZMYND8; HIC2; ZBTB18; MAGED1; POU2AF1; SMAD1; IKZF1; TCFL5