Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11603	Afatinib	GSE70138	HME1	Human	24h	1.11uM	EID0015

Response Information :

Types	Number	Response transcription factors
Up-regulation	66	E2F2; PPARG; NFKBIA; TSC22D3; TFAP2A; KLF11; CREG1; CREBL2; SP140; ID3; VGLL1; FOXF2; TP53; SOHLH2; TCEA2; ELF4; PCGF2; NFE2L1; MKL2; MEIS2; ZBTB16; TFDP2; HOXB5; SMAD6; ZNF623; MITF; SPIB; PBX1; MYCN; HOXB7; HOXB6; PRDM2; MXI1; SOX13; TRIM29; TFEC; ATF3; PIR; TRIM16; ARID5B; HMGN3; RXRA; TCF7L1; TRIM22; ID1; CEBPD; ZBTB20; SP140L; SIX3; KAT2B; BCL11A; TWIST1; TXNIP; FOXF1; MSX1; MEIS1; KDM5D; GATA6; POU2AF1; ID4; HOXA5; TLE4; PDLIM1; ARNT2; TCF21; TLE1
Down-regulation	38	ETS1; FOSL1; EGR1; BCLAF1; PRKDC; HMGA1; NFKB1; ORC2; TRRAP; ZNF281; SMAD7; YWHAB; NR4A2; RCOR1; HMGA2; ELK3; NKX3-1; RUVBL2; SFPQ; NRIP1; ING3; IRX5; KLF2; ATF5; TFAM; ABL1; HIRA; CUX1; MAGED1; BAZ1A; ZBTB18; CHD7; JARID2; ZIC1; LEF1; ZBTB38; SOX9; BASP1