Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11574 Mk-2206 GSE70138 HME1 Human 24h 3.33uM EID0015
Types Number Response transcription factors
Up-regulation 118 CRYM; CALCOCO1; CCNH; ACTL6B; ZBED1; CUX2; MYBL2; ARID3A; HBP1; ZNF141; THAP7; HIC2; FOXJ1; ZNF117; HIPK2; ZNF74; SOX3; ZNF235; TEAD4; ZIC3; ZNF85; TRIB3; ZBTB44; BRWD1; ZNF623; ST18; FEZF2; BNC1; CREBL2; MAFG; ZNF219; ZNF180; BCL11A; PIAS1; NFATC4; MED15; ZNF682; SMARCA1; MNDA; ZNF75D; CBFA2T2; ELF4; ZNF124; TULP3; SOX18; RORC; LIN28A; HMX1; ZNF33B; HDAC9; ERBB4; SUMO1; CBFA2T3; THRA; ATN1; BACH2; ZNF500; E2F2; HOXB2; PRDM2; ZFP36L2; NAB2; ZFHX3; IRF6; ATOH1; ZBED2; SIX3; HHEX; NR5A2; SALL2; ZNF467; ZNF350; RORA; IRF9; ZNF232; ARNT2; MYRF; KLF11; ZNF423; ZHX2; SRCAP; HOXB6; SOX13; EYA1; PBX3; CDIP1; TCF7L1; ADRB2; SSBP3; CBX4; MYBL1; FOXA2; FOXF2; BARX1; KAT2B; HLF; ZNF43; TCEA1; MEIS2; NANOG; HOXD1; CREB1; VPS72; CERS4; DLX5; NFATC3; ARID1A; SOX17; SHOX2; ZIC1; ZBTB16; PAX6; CALR; TRIM22; ZNF91; SOX9; AEBP1; GATA6
Down-regulation 42 NRIP1; MYCBP; TSC22D3; HSF2; KDM2A; CRY1; SMARCA2; PRKDC; MED1; RBM14; ENO1; BAZ1A; BMI1; TSC22D2; HLTF; SREBF1; PIAS2; MAX; ELF1; HDAC1; YWHAB; BHLHE40; C1QBP; PPARG; ERBB2; DNMT3B; CTR9; TRIM16; TAF10; BRD2; RBPMS; HOXA5; HOXC6; FOSB; HTATIP2; HMGB3; SUB1; ETS2; PTTG1; MAFB; ZBTB38; SUV39H1