Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11573	Mk-2206	GSE70138	HME1	Human	24h	10uM	EID0015

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	IRF6; HBP1; CALCOCO1; ARID5A; ZNF117; FOXO4; SREBF2; PBXIP1; ZNF219; HHEX; CTBP2; RYBP; ST18; RORC; ZNF611; FOXI1; TSHZ2; INSR; MAF; AES; ZNF75D; PNRC1; CBFA2T3; ATOH1; KLF4; EVX1; MNDA; SCAND1; CBFA2T2; CERS4; CEBPD; EMX2; TRIB3; AR; OSR2; WNT4; MEF2D; EPAS1; CBX7; PAWR; KLF11; HDAC9; ZBED2; ZNF331; ZFP36L2; ZNF91; ZNF160; ZHX2; ZFP36L1; IRF9; TULP3; DLX2; SRCAP; MEIS1; ZNF43; TXNIP; JUND; NFATC4; ZKSCAN1; BCL11A; ARNT2; FOXN3; NFATC3; LITAF; RBPJ; TGFB1I1; EHF; BHLHE41; FOXA1; TGFB1; TFAP2C; KLF6; HOXD1; BTG1; JUP; PBX3; IRF8; ETS2; ZFPM2; DACH1; INSM1; BASP1; AEBP1; TOX3; WT1; MYRF; PEG3; ESR1; ERBB4; TSC22D1; CITED2; GATA6; SOX9
Down-regulation	60	MYCBP; EZH2; ATF6; WHSC1; MED4; PSMC3IP; BLM; BRCA1; RUVBL2; XRCC6; ENO1; ALX1; CCNA2; ID1; PRKDC; MTDH; BCL3; RBM14; CENPF; CCDC59; NUP62; SOX10; TRIM28; TOX; KLF10; PIR; SFPQ; BIRC2; CBX3; SIX1; SMAD3; ASH2L; HOXB7; HMGB2; HOXC10; HMGN3; MED1; HOXA5; ID3; PTTG1; SERTAD2; SLC2A4RG; BAZ1A; PITX1; LEF1; MAGED1; HLTF; BHLHE40; EYA2; SUB1; NRIP1; TAF10; THAP11; SMAD1; HOXC6; SUV39H1; BMI1; HEY1; IKZF1; SSBP2