Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11569	Palbociclib	GSE70138	HME1	Human	24h	1.11uM	EID0015

Response Information :

Types	Number	Response transcription factors
Up-regulation	61	SOX4; ZNF516; ZMYM2; TBX3; NCOR2; KLF4; SREBF1; SOX15; ZNF721; CDYL; TCEA2; PTRF; BHLHE41; DMTF1; ZNF140; DLX2; DACH1; MBD2; NR4A3; ZNF160; FOXF2; MEIS1; ZNF665; ZNF611; ZSCAN31; NR2C1; PPARGC1A; FOXA2; TRIM29; MAFF; ZSCAN18; CREM; IRX5; SOX10; DNAJC1; ZIC1; BCL11A; MAF; HSBP1; BHLHE40; IRF6; IRF7; TSC22D2; SMAD2; ZKSCAN1; ZNF195; ATF3; FOSL2; SOX17; LOXL2; HTATIP2; DLX5; SATB2; ESR1; TRPS1; MECOM; EMX2; JUP; ZNF91; BASP1; GATA6
Down-regulation	62	IKBKAP; EZH2; FOXM1; CCNA2; MYBL2; CDK2; E2F8; DNMT1; CENPF; CHAF1B; HMGB2; WHSC1; YEATS4; TEAD4; ZNF146; KAT7; BRCA1; ZNF184; CBX5; WDHD1; TAF5; RBL1; GMNN; PSIP1; BRIP1; CD3D; PTTG1; GABPB1; DEK; POU4F1; NFE2L3; TTF2; BAZ1B; BRD8; TRIM28; MYBL1; CNOT2; HHEX; SAP30; SSX1; BCL11B; MNDA; PLAGL2; TBL1X; ZBTB18; CREG1; RUNX3; HOXB7; SMARCA1; SIAH2; ARID1A; SUB1; CALR; PITX1; HOXC6; SOX11; THAP11; KDM5D; SUV39H1; CITED2; CREB1; LEF1