Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11568	Palbociclib	GSE70138	HME1	Human	24h	3.33uM	EID0015

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	ZNF419; EGR1; SOX4; ZNF586; ZNF711; ZNF415; NCOA2; ZSCAN18; HBP1; BHLHE41; ZNF134; ZBED2; ZNF304; ZNF426; ZNF544; E2F5; STAT2; NLK; NR1I3; KLF6; PPARGC1A; ZNF665; ZNF135; ZNF264; WWP1; ZNF211; TOX; ZNF667; SND1; ZNF551; ZFP69B; HDAC9; ZNF468; ZNF329; MXD4; TWIST1; PTRF; TCEA2; SMAD7; ZNF606; ZNF587; ZNF266; ZNF91; SIN3B; ZNF217; PNRC1; COPS5; ATF4; ID1; NCOA4; NR1H3; FOXO1; HOXB2; HLF; JUND; ID4; ATF3; ZNF93; YAP1; DLX2; SP110; MYCN; MAFF; ZNF195; IRF7; NRBF2; TRPS1; SMAD6; TRIM29; ETV5; ZIC1; FOXG1; ID3; IRF4; TSC22D1; IRF6; NR2F1; TRIM22; TFAP2C; POU2AF1; ZNF512B; TXNIP; SOX17; ZNF232; VPS72; ESR1; PEG3; IRF9; GATA6; MYRF; WT1; TOX3
Down-regulation	64	EZH2; FOXM1; CCNA2; CENPF; CDK2; HMGB2; SSRP1; MYBL2; BRCA1; TFDP1; NRIP1; WHSC1; HMGXB4; UBP1; PTTG1; ITGB3BP; GABPB1; MXD3; DEK; BAZ1B; TBL1XR1; PSMC3IP; E2F8; YBX2; CBX5; ING3; HMGB1; RBM14; HLX; RRN3; KLF4; GMNN; BCLAF1; ARID1A; PITX2; CBFA2T2; RNF138; TBL1X; RUVBL2; NKX3-1; BAZ1A; EYA1; PHIP; TOB1; TRIB3; HMGB3; PSIP1; MYBL1; AFF1; SATB2; MYB; HHEX; HOXB7; CTBP2; FOXF1; FOXA1; ZBTB18; HOXC6; SMAD1; SUV39H1; FLNA; KDM5D; SATB1; BASP1