Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11567	Palbociclib	GSE70138	HME1	Human	24h	10uM	EID0015

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	SOX4; ZMYM2; TCEB2; HOXB1; CBFA2T3; SOX3; GBX1; CDX1; KLF4; RUNX1; ZNF136; ZNF611; ELF4; WWC1; BAZ2B; ZNF117; CTBP2; ZNF91; ZNF768; HNF1A; GATA6; ATOH1; MXD4; AR; BCL11A; DLX2; THAP4; ZBED2; CREB3L1; TBX3; DACH1; PLAGL1; CREM; ZNF665; ZNF160; MYCN; MNDA; JAK2; NFE2; HOXB5; ZNF93; FOXF1; PAWR; CUX1; SP100; PRDM12; NR0B2; LDB1; NFATC1; CREBL2; PHF1; SOX17; BHLHE40; TFEC; WNT4; SATB2; MYCL; ST18; MYB; HOXD1; ZNF467; NFATC4; TXNIP; MAF; CUX2; ZSCAN18; INSM1; MYRF; NPAS2; MXI1; TRIB3; EMX2; BARX1; ZKSCAN1; ZNF652; WT1; ERBB4; MEIS1; ID4; BHLHE41; HOXB2; PAX6; CREB1; SOX9; TSC22D1; TOX3; JUP; ZBTB38; ARNT2; ESR1
Down-regulation	85	EZH2; CCNA2; FOXM1; CENPF; WHSC1; BRCA1; SSRP1; CDK2; FOSL1; HMGB2; HES1; TFDP1; DNMT1; MYBL2; XRCC6; PTTG1; CBX5; HMGB1; KAT7; DEK; E2F8; PSIP1; RBM14; SAFB2; RBL1; PARP1; PSMC3IP; ING3; PA2G4; TAF9B; NUP62; BLM; CBFB; BCLAF1; WDHD1; PRKDC; POLR2A; BRD8; NFIB; BAZ1B; TRIM28; YEATS4; BAZ1A; MED1; RUVBL2; PIR; HOXC10; HOXC6; CALR; BRIP1; SAP30; HMGA1; SLC2A4RG; FUBP1; HNRNPD; GTF2I; GABPB1; TFAM; CARHSP1; DNMT3B; IRX5; CHD1; FOXO1; AFF1; MSX1; HOXB7; BCL11B; ID3; MYBL1; RBPMS; BRD2; CNOT3; NR2F2; HLTF; PITX1; RBBP8; MAFB; HMGB3; FOXD1; NR1D2; BMI1; SUV39H1; TWIST1; LEF1; ID1