Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11561 Osi-027 GSE70138 HME1 Human 24h 10uM EID0015
Types Number Response transcription factors
Up-regulation 103 SOX4; CDK7; HBP1; ZNF688; STAT2; ZBTB17; ZBED2; ZNF536; PPP1R13L; HNF4G; NFATC1; BPTF; CREBL2; EZH1; COPS2; PROX1; SP100; TGIF1; PRDM14; TAF7; SOX15; RYBP; KLF7; BCL11A; PFDN5; TSG101; HDAC5; PBXIP1; HMGA2; SAP18; TGFB1I1; TSHZ2; LYL1; SPEN; ZNF264; HHEX; NR2C1; ZNF91; ST18; IRF6; TFEC; ZNF611; OVOL2; FOXN3; ATF4; INSR; ZFP36L2; RUNX1; ZNF589; MXI1; SCAND1; SUPT3H; ZNF281; BACH1; CREG1; HMBOX1; ZNF573; PHF20; IRF7; TOB1; PAWR; ZSCAN18; TCEA1; VDR; UBE2B; MAF; APEX1; TCF7; MAFF; NR1H2; HIVEP2; CUX1; TDP2; CBFA2T3; ZNF160; TBX3; KLF6; BACH2; ZNF195; RBPJ; GATA6; MYRF; MYB; ZKSCAN1; ELF3; BTG1; EHF; HOXD1; INSM1; BHLHE41; ZHX2; TRIM22; ID3; CREB1; RBPMS; AEBP1; IRF9; BASP1; SOX9; TXNIP; JUP; KLF5; TLE1
Down-regulation 57 MYCBP; EZH2; TFDP1; MYBL2; CCNA2; CDK2; WHSC1; RUVBL1; FOXM1; PSMC3IP; PDLIM1; XBP1; DNMT1; PIR; SFMBT1; ZKSCAN5; HMG20B; NFIL3; POLR2A; RNF4; CCNC; SUB1; SLC2A4RG; PRKDC; RBM14; BRCA1; NCOA1; PTTG1; CENPF; HOXC10; BLM; TRIM24; RUNX3; TRIM32; YWHAB; FOSL2; HMGB3; CALR; HMGN3; SFPQ; MAGED1; RXRA; BHLHE40; FOXG1; HIC2; HOXC6; STAT3; CHD7; TGFB1; FOSB; BMI1; PBX3; SUV39H1; ZFP36L1; LEF1; ASCL1; TOX3