Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11558 Pd-0325901 GSE70138 HME1 Human 24h 0.37uM EID0015
Types Number Response transcription factors
Up-regulation 111 NFKBIA; ATF3; HES1; ARID5B; KLF7; PPP1R13L; IRF6; KDM4C; FOXO3; KLF4; ZNF536; ZNF768; PHOX2B; TCEA2; HBP1; PNRC1; RNF10; TSC22D3; MAF; BPTF; WNT4; PBX1; TOB1; HDAC5; ZNF423; BACH2; CREG1; RFX5; RXRA; TFDP2; PBX3; CALCOCO1; ADRB2; RELB; OSR2; COPS2; STAT1; MXI1; JUND; SREBF1; IRF9; TCF7L1; ZNF350; SETDB1; ID3; TRIM16; FOXI1; GLI3; PFDN5; YEATS2; BRD4; BTG1; INSR; ELF3; ERBB2; TP63; CSDC2; BCL6; GATA3; TRIM29; ZNF195; CUX1; MBD2; ATF4; PBXIP1; TRIM22; SETD2; GRHL2; CBFA2T3; TBX3; MYCL; MEIS2; RORA; MITF; ZMIZ1; HDAC9; ZSCAN18; CREB3L1; DLX5; SERTAD2; DACH1; PHF20; EPAS1; PAWR; TCF7L2; AEBP1; ISL1; HHEX; ZHX2; JUP; ZFP36L2; VDR; HTATIP2; SIAH2; MYRF; TLE1; BNC2; PEG3; TCF4; LITAF; SALL2; MEIS1; CREB1; ARNT2; TRIB3; PDLIM1; TCF21; ZNF91; GATA6; ID1; SSBP2
Down-regulation 75 FOSL1; HMGA2; EZH2; ETV1; MYC; BRCA1; WDHD1; EGR1; DNMT1; SFMBT1; EGR3; PSMC3IP; XRCC6; RUVBL1; PPARG; RBL1; WHSC1; PRKDC; HMGA1; EGR4; BRCA2; TAF5; CCNA2; ENO1; HMGB1; HMGB2; BLM; BAZ1A; BCLAF1; E2F3; MTF2; BATF3; ZNF22; ETV5; NKX2-2; TAF9B; WDR77; RBM14; ETV4; TOPORS; TBL1XR1; MED23; ELK3; TRIM28; TFAM; ING3; MSX1; CENPF; APEX1; ILF2; ZNF721; NUP62; RBBP4; HOXC6; HOXB7; ARNTL2; ZNF160; MYBL1; NFAT5; SUV39H1; HMGB3; PTTG1; HOXC10; ZBTB18; PSIP1; WWTR1; KDM5D; NPAS2; CTR9; BMI1; VGLL4; HLTF; KLF2; MYB; TCFL5