Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11548 Saracatinib GSE70138 HME1 Human 24h 0.04uM EID0015
Types Number Response transcription factors
Up-regulation 17 E2F2; HOXA1; PIR; HDAC1; CEBPD; GATA3; TOB1; MAFB; TFDP2; TBX3; RBBP8; EGR3; ASCL1; JUP; MYB; MYRF; TOX3
Down-regulation 32 YBX1; SMAD7; ZNF281; SIX1; KDM5D; ZFPM2; NKX3-1; ZNF331; SMARCA1; ZNF22; ELF5; FOXN3; MAGED1; EYA2; KLF9; MEIS1; EHF; TCF7L1; ZIC1; SNAI2; ZNF512B; THAP11; TGFB1; TRIP6; CREB1; ELK3; SOX11; TCF4; EMX2; ID1; PEG3; IKZF1