Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11535 Fostamatinib GSE70138 HME1 Human 24h 0.12uM EID0015
Types Number Response transcription factors
Up-regulation 227 HES1; RFX5; HDAC6; YEATS4; EGR1; NKX2-1; GTF2A1; WHSC1L1; ZMYM2; OLIG2; MLX; HOXA1; POLR3F; YY1; ZNF208; DMRT1; TAF1D; ZNF79; ZNF222; ZNF10; ETV1; ZBTB44; FOXJ1; ZNF236; ZNF324; ZNF675; ZNF552; SP4; TAF7L; RUNX3; ASH1L; ZFY; ZNF331; CARF; MBD4; AFF4; MDM2; ZNF107; ZNF197; FOXE1; SP140; ZNF711; BRWD1; ZBTB43; SFMBT1; ZNF516; CEBPD; TADA2A; IKZF2; TRIM33; IRX5; PPARGC1A; TEAD1; ARID3A; ZNF292; SOX4; PHF8; SKIL; SAP18; RCOR3; NR2C2; KDM5D; ZNF764; ID3; KLF12; ZNF669; ZKSCAN7; WDHD1; SSX1; PAX5; ZNF257; SPIB; ZNF141; SUV39H2; TAF12; LHX2; ZNF253; ZNF480; ZSCAN16; ZNF136; SOX3; ABL1; LIMD1; ZNF135; SKI; BATF; PML; GABPA; ZNF274; NKX3-2; MED7; ZFP69B; HR; SNIP1; CCNT1; ZNF254; TRIM25; PAX2; MXD4; IRF5; RARA; E2F5; FOXG1; ID2; BRCA1; ZNF14; ZNF606; IL16; FOXF2; MBD2; ZNF528; ZNF468; EYA3; TMF1; HSF2; TRIM22; ZSCAN12; HDAC9; E2F3; RFX7; HCFC2; PIAS2; ESRRA; CALR; MTF2; IRF8; DNAJC1; CREM; ZNF267; PEX2; IKZF5; ZNF85; RBL1; YEATS2; PHIP; ADRB2; ZNF84; CUX2; NRBF2; ZNF205; TOX; MNX1; FOXL2; EGR2; ZSCAN18; PIAS3; WWP1; ZBTB32; PSMC3IP; ZNF350; ZNF226; FOXF1; POU2AF1; MEF2D; CITED1; ZSCAN31; BCOR; TCF3; UBTF; PIAS1; NCOR2; BRIP1; TOPORS; ETV5; MITF; ZNF268; ZNF432; SMAD7; POU2F2; ZNF195; ZNF580; ZNF430; ZNF532; ARID4B; SIM2; STAT1; CHD7; ELF1; SALL2; RSF1; SPEN; ING3; ZNF264; CRYM; NR2F1; SP140L; ZNF93; RERE; AFF1; ANKRD1; SETD2; GTF2I; NEUROD1; ASCL1; SMARCB1; NR4A2; TFAP2C; ZNF551; IRF4; SMAD6; STAT3; SALL1; KLF9; SPDEF; RBPJ; ZNF160; ZNF12; ST18; ERBB4; CREB1; MYBL1; HTATIP2; MSX1; ZNF232; MYCL; HOXC10; MAGED1; FOXC1; BBX; ID4; PBX1; HOXD1; ZIC1; INSM1; PDLIM1; HOXA10; BASP1
Down-regulation 112 IKBKAP; TCERG1; NFKBIA; YWHAB; PHOX2B; SP2; PCGF1; CNBP; PHF20; TEAD4; BRD7; CTCF; ZMYND8; CCNC; ETS1; PPARD; VGLL1; FOXM1; MED16; PA2G4; RUVBL2; HOXC6; PHOX2A; CBFA2T2; TBL1XR1; WWTR1; ZNF423; NELFB; HAND1; TRRAP; NR2F6; DEAF1; ZMIZ1; ASXL1; TAF6; TOB1; RBM39; PNRC1; SCAND1; NFIB; AEBP1; ZZZ3; TRIM28; HIRA; CHD4; CREG1; ZKSCAN1; FOXO3; CDC5L; BIRC2; GTF2IRD1; PSMC3; CTBP1; ERCC3; CRY1; BCL11A; TERF1; TRIM16; RXRG; CBX7; SERTAD2; CENPF; RBFOX2; HMGA2; PBX3; NFE2L3; ZNF593; NR0B1; TSC22D1; PTRF; BCL11B; THAP11; FOXO1; HOXB6; NOC2L; MAFB; TRIB3; DLX5; HMGB2; KLF13; DNMT3B; MED24; TAL1; HOXB7; SIAH2; KLF4; SMAD3; CD3D; LITAF; CTBP2; DLX2; ELK3; FOXN3; KLF11; ZFPM2; ZFHX4; YAP1; NKX3-1; SOX9; PIR; HOXB2; HOXA5; GATA6; EYA2; ESR1; AHR; LEF1; EHF; KLF5; SMAD1; MEIS2; ZFP36L1