Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11502 Geldanamycin GSE70138 HME1 Human 24h 0.04uM EID0014
Types Number Response transcription factors
Up-regulation 279 FOXO4; PCBD1; CALCOCO1; ZKSCAN4; SOX4; MEIS2; ZNF44; HINFP; NR1H2; BPTF; ZNF33B; ELF4; VPS72; ARID5B; BRD4; BARX1; PNRC1; SCMH1; CDK7; ZHX2; PRDM2; ZNF654; SETDB1; DYRK1B; PBXIP1; IKZF1; HBP1; ZNF91; ZNF394; MED12; VENTX; SUPT7L; RING1; ZNF184; ZKSCAN1; ZNF362; RSF1; HOXA5; TLE4; HDAC9; ZNF225; MEOX1; APBB1; HDAC4; LDB1; ZNF423; ZNF268; POU2F1; ARNT; KDM5B; SIRT2; CSDC2; MLXIP; ZSCAN9; ARID5A; MAK; GCM1; EYA1; ING4; SALL2; ZNF214; GFI1; RLF; BAZ2B; ZSCAN31; TCF15; FOXN3; LYL1; ZNF536; PFDN5; SIX6; ZNF3; ZNF136; SIM1; HDAC5; ZNF345; EZH1; ZBTB44; DBP; ZNF76; TULP3; SOX17; TEAD3; ZNF500; AR; ZNF224; KAT2B; EP300; PHF1; ZKSCAN3; CIITA; IRF1; ZNF223; CBX7; HMBOX1; ZNF12; TOX; CHD4; ZNF512B; TCEA2; ZNF529; MNDA; ZNF337; ST18; ZNF212; NCOA2; MECP2; RELA; HOXD1; KAT5; BRD8; RNF111; CIR1; RAX; HMX1; JUP; ZNF350; ZNF112; ZNF140; SRY; FLI1; JAK2; SHOX2; TSG101; KDM4C; FOSL2; PCGF1; TCF7L2; USP21; MED23; CBFA2T2; ZNF34; ZSCAN16; BCL11A; ZNF606; PIAS1; ZNF384; TCF21; ZNF304; E2F8; OVOL2; OSR2; SOX3; SIAH2; TRIB3; KMT2A; MYCN; ADNP; CREBL2; SP100; EMX2; IRF9; ZNF133; ID3; ZNF14; ZIC1; LITAF; CDIP1; SUPT5H; L3MBTL1; NFYC; POLR3C; MED17; TAF4; SP140L; YEATS2; HIVEP1; HOXB2; ZNF195; PIR; IRF4; SUPT4H1; PIAS4; KLF13; PAX6; ZNF682; MEIS1; ZNF671; TGFB1I1; SOX2; TFDP2; VEZF1; TFEC; SOHLH2; ZNF467; ZNF711; WNT4; ZNF248; KLF3; ZFHX3; RORA; HIVEP2; ZNF264; ZNF573; NR1H4; UBE3A; CXXC1; PDLIM1; CAMTA1; TAL1; SP2; IRF6; CREG1; SND1; ZNF667; REL; NCOA1; KAT6B; THAP4; PBX2; CITED2; ZMIZ1; KLF7; MZF1; ZNF623; ZNF141; SIN3B; ZNF219; AEBP1; ATF3; HOXB5; INSM1; TFAP2A; ZMYND8; PLAGL1; MYRF; TFAP2C; MXD4; TP53; ATF4; PBX1; ZNF415; SPI1; MEOX2; NFATC4; SPDEF; ARID4B; INSR; ZNF217; TAF11; MYT1L; SSBP2; PHIP; ZNF85; PEG3; ZSCAN18; SOX13; ZNF232; ZNF160; WT1; TCF7L1; HOXD3; CDK8; ESRRG; RERE; NFAT5; MECOM; BNC2; NR4A1; TWIST1; ZEB1; TCF4; ARNT2; MXI1; ZNF611; FOXO1; ID4; ASCL1; PCGF2; ZNF652; PCGF3; ZFPM2; NEUROD1; NCOA3; ZMYM2; GATA6; ELF3; HMG20B; POU2AF1
Down-regulation 90 FOSL1; HMGA2; MYC; RUVBL1; PARP1; CBFB; MYCBP; ETV1; HNRNPD; TSC22D3; EGR1; EDF1; TFDP1; RBM14; PMS1; PSMC3IP; NFIL3; DNMT1; XBP1; GTF2A2; SUV39H1; CEBPB; ELK3; ITGB3BP; NELFB; DRAP1; TAF9; PTTG1; PIAS2; SNAI2; ENO1; BRCA1; PREB; DNMT3B; RNF141; HSBP1; YWHAB; BLM; CTNNB1; RBBP4; TCFL5; PTRF; BHLHE40; C1QBP; CALR; SOX9; BAZ1B; GATAD2A; DDX5; SAP30; XRCC6; NEDD8; ING2; DNAJC2; PPARG; JUN; EGR3; NUP62; HTATIP2; HMGB2; BCLAF1; NFKBIA; RNF14; EGR2; BIRC2; HOXC6; MNAT1; PRRX1; ZBTB18; SERTAD2; UBE2I; SFPQ; HMGA1; KLF6; ZNF532; TSC22D2; RBBP8; HMGB1; TBX3; MYBL1; ID1; KLF9; SMAD3; IRX5; TAF10; MSX1; STAT1; KLF10; ZBTB38; ETS2