Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11497 Geldanamycin GSE70138 HME1 Human 24h 10uM EID0014
Types Number Response transcription factors
Up-regulation 145 PCBD1; FOXO4; CALCOCO1; CDK7; PHF1; PRDM2; TEAD3; ZSCAN31; OSR2; SOX4; DDIT3; PBXIP1; ARID5B; CITED2; POU2F1; BPTF; CSDC2; BAZ2B; SIX3; PAX8; ZNF16; HOXA5; HDAC5; SREBF2; HINFP; PNRC1; SIM1; TCF15; ZNF44; HBP1; TOX; CREG1; CIR1; MED17; KAT5; KMT2A; ZNF337; BRD4; SIX2; HMBOX1; MEIS2; TLE4; SMARCD3; PFDN5; HMGN3; EYA1; ZNF91; MZF1; ZNF175; JUND; HIPK1; WT1; NFE2L1; NAB2; BRD8; ZNF358; WNT4; PHIP; CHD8; CDIP1; GATA6; TCF21; FOXI1; AIP; ERBB2; CITED1; AR; SETDB1; PBX3; SP2; NCOA2; PIR; ZNF224; NR4A1; ATF3; ATF4; SIN3B; CBFA2T2; TP53; MAZ; LITAF; MAML1; MITF; CBX7; ZHX2; NFAT5; ARID4B; RORA; STAT6; PAWR; UBE2B; AFF1; BTG1; ING4; AEBP1; IRF9; HEY1; BRD2; TBX2; CERS4; INSR; ZNF117; NR2F2; FOXN3; CERS6; FOSL2; KLF11; ZNF160; ELF4; SMAD6; ELF5; NCOA3; ERBB4; ZNF611; NR4A3; RFX5; ZNF721; HOXC6; TRIM22; STAT4; ZNF232; PCGF2; HOXC10; ZNF304; HOXD3; TLE1; ZMIZ1; ZNF165; SOX11; ZNF331; EMX2; CREB3L2; BNC2; PEG3; TCF7L1; HMG20B; MXI1; CUX1; MEIS1; TRIM29; MAF; CREB1; POU2AF1; TOX3; SSBP2
Down-regulation 80 HMGA2; FOSL1; MYC; ELK3; RUVBL1; MYCBP; TSC22D3; HES1; PARP1; DNMT1; SUV39H1; MYBL2; PMS1; CCNA2; SSRP1; TFDP1; TERF2; C1QBP; HNRNPD; PPRC1; BRCA1; ORC2; ZNF281; HMGA1; XBP1; NRIP1; ETV1; ABL1; NFIL3; RBL1; WDHD1; SATB2; BHLHE40; CBFB; WHSC1; SMARCA4; ITGB3BP; ZHX3; GCFC2; KLF9; DRAP1; YEATS4; EGR1; NFX1; PA2G4; SNAI2; MAFF; ZFP36L2; ETV5; SOX9; ZBTB16; LOXL2; ENO1; RUVBL2; DMTF1; GTF3A; JUN; SMARCA1; ID1; ZBED2; ZBTB18; BHLHE41; RAN; TFEB; CTNNB1; TSC22D1; BASP1; HLTF; MNAT1; PRKDC; SMAD1; ID3; PPARG; MSX1; KDM5D; TRIP6; ETS2; MYBL1; ESR1; ZBTB38