Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11484	Mitoxantrone	GSE70138	HME1	Human	24h	0.04uM	EID0014

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	PSMC3IP; POLR3F; DYRK1B; SIM2; MEF2D; PHIP; NPAS2; ELK1; GTF2I; IRF5; SIRT2; WWC1; CREM; HDAC7; TSC22D1; BAZ1B; ELK4; CBFA2T3; ZBTB1; ZNF536; NKX2-1; TBX2; FOXC1; DMTF1; NAB2; SMARCA2; ZSCAN9; TRIM33; TSC22D4; AHR; SMARCA1; BRIP1; DLX2; TAF7; ADNP; RFX5; CRYM; MED23; PKNOX1; LMCD1; E2F8; BHLHE41; ZNF133; NR2F1; ZNF266; NLK; ZNF189; CEBPZ; HSF2; ATF5; EGR2; ING2; HSBP1; STAT4; ZKSCAN7; PBX3; SERTAD2; BAZ2B; POLR2A; TTF2; NKX3-1; RERE; NAB1; HMGN3; DDX5; IRF7; E2F3; MEIS1; NFATC3; INSM1; AFF1; TRIM16; BMI1; NR4A1; ZNF331; TOB1; MYRF; SPIB; NCOA3; NR0B1; RUNX1; HLTF; MTA1; STAT1; ETS2; IRX5; ZBTB18; MAGED1; CREB1; PAX5; EMX2; LEF1; ASCL1
Down-regulation	105	HMGA2; TCERG1; TCEA2; HNRNPD; TCF7L2; HMGA1; DNMT3B; TCEA1; TLE1; NR5A2; SFPQ; HDGF; ARRB1; ISL1; POU2F1; PA2G4; LZTS1; KLF7; PEG3; NR1I2; CCNC; LOXL2; RXRG; FLI1; ARNTL2; SOX17; CDX1; ZFP36L1; KLF11; MYT1L; FOXI1; TERF1; LIN28A; TGFB1I1; CDK9; C1QBP; ARID1A; HIRA; YAP1; FOXA2; EP300; HOXA7; MDM4; CBX3; ID3; KLF9; ENO1; JUP; HIC2; MEIS2; TGIF1; PPRC1; PRRX1; ZNF573; CHD4; GATAD2A; APEX1; PITX1; BIRC2; KLF6; FOXO1; SMAD2; MSX1; ZEB1; IFI16; MEOX2; KLF5; CARM1; CAPN15; ZNF91; FOXM1; ZNF423; HMGB2; RYBP; RORA; NR3C2; NCOA2; HMGB1; HOXA11; SOX13; PBX1; SNAI2; NR2F6; VPS72; NFE2L3; SMAD7; PLAGL1; HOXB6; ZNF232; BRD4; OSR2; SMAD1; ZMYND8; ELK3; TOX; FOXF1; TBX3; RBPMS; DLX5; MAFB; MECOM; ATF3; ZSCAN18; HOXA10; ZNF586