Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID11483	Mitoxantrone	GSE70138	HME1	Human	24h	0.12uM	EID0014

Response Information :

Types	Number	Response transcription factors
Up-regulation	85	FOS; EGR1; FOSB; ZNF165; PPP1R13L; NKX2-1; HDAC9; ID4; ZSCAN16; SKIL; ZNF512B; TRIM29; BLZF1; RSF1; SALL1; DMTF1; STAT3; TMF1; ABL1; CCNE1; FOXE1; CSDC2; BAZ1A; BACH2; HOXD1; BCOR; MAF; MYB; ZHX2; NR4A1; JUN; HIVEP2; WWP1; ARID5B; TRIP6; EYA1; ERG; GATA6; SPI1; NFATC1; PITX2; MLXIP; ZEB2; ZNF302; ZNF267; NR4A2; ARID4A; HOXA5; ATF3; EHF; TP53; VGLL4; SOX17; EGR3; TRPS1; MITF; ID3; BAZ2B; IRF6; DACH1; ZFHX4; ESR1; FOXO1; VDR; SPEN; ELF5; LMCD1; NPAS2; GRHL2; MEIS1; ASCL1; RUNX1; FOXG1; FOXF1; HOXC6; TBX3; THAP11; KLF5; MAGED1; LEF1; WT1; ZIC1; ZFP36L1; TOX3; TWIST1
Down-regulation	67	TRIB3; TCERG1; RXRA; MLLT10; TCEA2; CNBP; CNOT2; NFIC; HMGA2; PSIP1; BMI1; PIAS1; IKZF5; SUMO1; GTF2I; ZNF384; ARID1A; SUB1; ZBTB11; TAF9B; AR; CREB3L1; AES; CCNC; CALR; ATF4; ETS1; HMGB2; SERTAD2; NR2F6; GTF3A; STAT6; CEBPB; ZEB1; TFDP2; TEAD4; CTNNB1; DNAJC1; TGFB1; KAT2B; NEUROD1; SMAD1; ASH2L; NR2F2; DDIT3; TCF7L2; INSR; ZMIZ1; TP63; BCLAF1; HLF; LOXL2; HOXA11; HOXB6; CD3D; PEG3; NANOG; BHLHE40; BASP1; TCF7; HOXA10; NFIB; FLNA; MECOM; MYBL1; FOXC1; ZNF586