Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11450 Torin-1 GSE70138 HME1 Human 24h 3.33uM EID0014
Types Number Response transcription factors
Up-regulation 120 SMARCD2; SOX4; MYC; FOXO4; MAF; NR1H2; TGIF1; HMGA2; PPP1R13L; CDK7; HBP1; MNT; MXI1; PPARD; PRDM4; ZHX2; TGFB1I1; BPTF; BTF3; BCL11A; SND1; AES; ZBTB43; PNRC1; ARID5A; CALCOCO1; HAND1; ZNF91; ZNF44; KAT2B; TSC22D1; IRF6; ZNF394; EZH1; LITAF; NFKB2; JUP; GTF2F1; STAT5B; ZNF136; ZNF426; TSG101; RCOR3; FHL5; ZNF580; KLF9; HDAC5; ZNF611; ARID5B; TLE1; HIVEP2; PCGF1; MEIS1; PBXIP1; TP63; ZNF224; FOXN3; EP300; FOSB; ZFHX3; JUNB; ZNF667; SETDB1; CREBL2; GTF2IRD1; TCEA1; HMBOX1; ZMIZ1; MTA1; NFIL3; ISL1; EHF; ZNF665; CBX7; FOXO3; ZNF266; ZNF160; KLF3; YBX1; ADRB2; KLF11; ELF4; ETS1; MAFF; MLXIP; APEX1; PAWR; FOXE1; SMAD7; KLF6; SSBP3; LIN28A; MED24; KLF4; CHD7; EMX2; ZNF217; ATN1; NCOA2; NR1D2; BTG1; ZNF83; KAT6B; KLF5; NR4A2; ERBB2; MITF; OSR2; AEBP1; ZMYM2; PDLIM1; CREG1; GATA6; KDM5D; THAP11; TWIST1; ZSCAN18; WT1; TBX3; PAX5
Down-regulation 68 MYCBP; CCNA2; MYBL2; EZH2; CDK2; PARP1; SUV39H1; RUVBL1; PTTG1; BRCA1; DNMT1; SUB1; RBL1; FOXM1; CHAF1B; PSMC3IP; GTF2A2; RBM14; CENPF; CCNE1; WHSC1; WDR77; TFDP1; WDHD1; TFAM; BLM; XRCC6; EGR1; HMGB3; BAZ1A; ITGB3BP; HMGB1; ILF2; TAF9B; SMARCA5; MYBL1; BRIP1; MED7; PBX3; MAGED1; ENO1; SMAD1; XBP1; ACTL6A; TOX; MSX1; ZEB1; RBBP8; HMGB2; CBFB; RNF4; CBX6; CRY1; NFIB; ID1; SERTAD2; EGR2; MECOM; EGR3; TOX3; FOXG1; TRPS1; MAFB; ZBTB18; KLF10; HOXB6; SSBP2; ID4