Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11433 Zstk-474 GSE70138 HME1 Human 24h 3.33uM EID0014
Types Number Response transcription factors
Up-regulation 132 HMGA2; MYC; HDAC5; NR3C1; STAT2; JARID2; HDAC6; ID3; MNT; CALCOCO1; KDM5B; PPP1R13L; TSC22D3; HES1; TFDP2; NCOA4; RELB; BTF3; HBP1; RSF1; SUPT3H; FOXO4; TCEA1; ZBTB43; EGR3; BLZF1; WWP1; TERF1; TSG101; HDAC9; ETS1; MLLT10; IRF9; TRIM22; NR4A2; PBXIP1; ZNF516; NONO; ZBED1; UBE2B; WNT4; MAFG; EGR2; NCOR2; TGFB1I1; AIP; TLE2; BACH1; MYCN; SMAD2; SETDB1; ZNF711; SMAD4; PPARGC1A; MZF1; FLI1; ZNF532; ZNF268; IRF1; ZNF350; TRAK1; ADRB2; DBP; PLAG1; HIVEP1; KLF7; RUNX1; PFDN5; TRIP6; NCOA2; KLF13; ELK3; CREBL2; TGIF1; ELF1; PNRC1; FOXJ3; MAX; ATF3; MTA1; SMAD7; MNDA; SPEN; MAFF; SOX13; FOXN3; MAF; INSR; ZNF304; SOX17; CHD7; APEX1; ZNF432; TOX; FOSB; NR1H3; TFAP2A; CSDE1; ERG; TGFB1; TLE1; FOXF2; PDLIM1; JUND; PEG3; BHLHE41; ELF3; SALL2; DLX2; ZIC1; ZFPM2; RBPJ; CREG1; KDM5D; ZNF83; TCF7L1; BACH2; HHEX; PLAGL1; NR2F1; SOX11; CEBPD; OSR2; DLX5; ETS2; MSX1; DACH1; GATA6; MEIS1; POU2AF1; ID1; EMX2
Down-regulation 56 PCBD1; MYBL2; CENPF; TCERG1; EZH2; RUVBL1; MYCBP; CCNA2; SUV39H1; CDK2; DNMT1; GTF2A2; SSRP1; WDR77; BRD7; PSMC3IP; FOXM1; HOXC6; MYBL1; ILF2; NOC2L; MKL2; TFDP1; ARL2BP; ZNF423; C1QBP; CCNE1; ZNF200; BRCA1; RBBP7; SLC2A4RG; CARHSP1; BLM; CBFB; BBX; RAN; TRIB3; EYA1; ZNF652; HOXC10; CREM; BHLHE40; VGLL4; CTBP2; HMGB2; THAP11; NR2F2; MED24; EHF; LMCD1; TOB1; ELF5; MAGED1; MAFB; MYB; NFATC3