Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11432 Zstk-474 GSE70138 HME1 Human 24h 10uM EID0014
Types Number Response transcription factors
Up-regulation 152 HMGA2; MYC; FOXO4; SOX4; CDK7; BTF3; FLI1; MNT; MAF; KLF4; NONO; CREBL2; BPTF; PNRC1; TSG101; SUPT3H; HDAC9; TSC22D3; ZNF195; TFEC; ZNF91; ZNF426; HBP1; ZNF136; BAZ2B; POU3F2; TDP2; ZNF266; ZNF155; NFIX; HDAC5; INSR; HDAC4; RSF1; ZNF14; HIPK3; FOSB; PLAG1; ZNF536; ZNF33B; GTF2F1; FOXN3; MAFF; ZNF177; AHR; CITED2; RCOR3; MNDA; IRF9; RLF; BACH1; ADRB2; MAFB; ZSCAN9; NCOR2; FOXJ3; SAP18; SP110; YBX1; INSM1; NCOA4; ZNF432; ZEB2; PPP1R13L; ADNP; NR1I2; CTBP2; IRF6; MED23; FOXO1; AIP; EP300; BTG1; ZNF112; BCL11A; TRAK1; UBE2B; KLF11; ZNF117; CBX7; MEIS1; EMX2; KAT6B; EGR3; SP2; ZNF467; SP100; KLF6; MITF; PHIP; HOXD1; JARID2; ZNF219; ARID5B; GATA6; ELF4; CERS6; PPARGC1A; PFDN5; KAT2B; SOX17; SMAD2; BRD4; APEX1; NRBF2; NPAS2; ZNF83; HTATIP2; ZNF430; GTF3A; ZNF573; MXI1; NR4A2; TGFB1I1; STAT6; NR1H3; ATF4; MEOX1; DACH1; BRD2; IRF7; PCGF2; AES; HOXD3; ZNF32; NR1D2; ZMYND8; BHLHE41; CUX1; TCF7L2; ERG; TLE1; ERBB2; LMCD1; TFAP2A; HOXC6; CREG1; ELK3; MTA1; TAL1; MEOX2; HLX; COPS2; EGR2; IRF8; OSR2; TRPS1; WT1; TLE4; CREB1; CEBPD; MECOM
Down-regulation 60 MYCBP; MYBL2; CDK2; CCNA2; PARP1; EZH2; SFMBT1; GTF2A2; DNMT1; RUVBL1; SUV39H1; BRCA1; ITGB3BP; CCNE1; PTTG1; CHAF1B; PSMC3IP; FOXM1; BLM; RBM14; WDHD1; CALR; HNRNPD; YEATS4; RBL1; HMGB2; CENPF; PSMC3; PMS1; MYBL1; NELFB; SLC2A4RG; TFDP1; SMARCA5; ENO1; YWHAB; NUP62; WHSC1; CBX5; RAN; TRIM16; SMAD3; PA2G4; SUB1; BRIP1; MAGED1; CRY1; PRRX2; FUBP1; HMGB1; SFPQ; EYA2; ID1; HMGB3; LEF1; RBBP8; PBX3; HOXB7; MSX1; NFATC3