Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11426 Azd-7762 GSE70138 HME1 Human 24h 0.04uM EID0014
Types Number Response transcription factors
Up-regulation 44 NFYA; SIAH2; ZNF266; ALX1; SOHLH2; KLF9; TULP4; CDK9; ENO1; NKX2-2; CERS6; MTDH; DLX2; ATF3; ATF5; PAWR; ZFHX4; ZNF189; DDIT3; TOX3; FOXG1; TFAP2C; PBX3; ZBTB16; HOXA5; SREBF1; MYRF; SMARCA1; PAX6; SSX1; FOXC1; RBPMS; HOXC6; AFF1; TLE4; BMI1; TWIST1; HHEX; TRPS1; GATA6; HOXB7; MYB; LEF1; THAP11
Down-regulation 27 TGFB1I1; KLF7; EYA1; JUP; PKNOX2; TRIM22; HDAC9; TP63; CD3D; ELF3; TSC22D2; ZMIZ1; CTBP2; ZFP36L1; TBL1X; BCL3; PSIP1; IRF8; MYBL1; BASP1; FLNA; TRIP6; TCF7; TRIM29; TXNIP; GATA3; NFATC3