Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11425 Azd-7762 GSE70138 HME1 Human 24h 0.12uM EID0014
Types Number Response transcription factors
Up-regulation 76 RELB; SRF; SAP18; SIAH2; PIR; ZNF3; ZZZ3; BATF; ZNF45; GFI1; BCL3; ZNF654; ATF5; PGR; SETD2; SMARCE1; MAFG; TEAD3; RUNX3; ZNF131; CHD4; KLF4; ZNF140; BCOR; JUN; ZNF281; ZNF32; CEBPG; MEOX1; IRF4; SUPT4H1; CDIP1; FOS; RNF6; NFKB1; ZNF226; JAK2; ZNF274; KLF11; TBL1X; SP100; POU2AF1; EGR2; SOX10; PCGF2; RORA; FOXD1; GTF3A; E2F3; EMX2; HEY1; MITF; MEOX2; TFEB; ZNF432; IRF1; MAF; MYRF; ELF5; MAFB; ZMYM2; MXI1; ZFP36L1; HOXB6; FOXO1; COPS2; ATF3; EGR3; HOXC6; ASCL1; MSX1; HOXB7; PITX1; ESR1; THAP11; IKBKAP
Down-regulation 52 PDLIM1; RUNX1; CEBPB; CARHSP1; NR0B1; DNMT3B; NFE2; RUVBL2; PHF20; CBX5; CHD9; CRYM; ZMIZ1; AHR; URI1; VPS72; HDGF; CREG1; BCL11A; PFDN5; TBL1XR1; FOXF2; PSIP1; EPAS1; SCAND1; TSC22D1; BTG1; RBBP8; WWTR1; MEIS2; HDAC9; KDM5D; FOXC1; MECOM; DACH1; SERTAD2; ZNF217; YAP1; PAX6; NFIB; SOX9; ERBB4; FOSL2; ZNF91; MYBL1; IRX5; ST18; HMGA1; GATA6; ZIC1; ETS2; MEIS1