Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11409 Wz-4-145 GSE70138 HME1 Human 24h 10uM EID0014
Types Number Response transcription factors
Up-regulation 422 GATA2; DDIT3; FOXO4; PCBD1; PHF1; CIR1; RELB; DPF2; TBP; ZKSCAN4; SOX2; ZNF222; HINFP; HIC1; SIX5; PFDN5; ZNF408; ZNF195; CDK7; HBP1; FOS; MAK; NKX3-2; PRDM8; MXI1; ETV2; ZNF136; TULP1; TBPL1; ZNF426; ID2; HDAC5; RLF; HOXA5; ZFHX2; PAX3; NPAS1; APBB1; MEF2C; NFKB2; SNIP1; POU4F2; SIX6; SCRT1; FOXD3; VENTX; NACA2; ZNF10; RSF1; NHLH2; ZNF16; RBPJL; AIP; POLR3F; TCF15; FOXB1; L3MBTL1; ZNF212; DMRT1; CDX4; ZNF362; NR5A1; HOXA6; IKZF3; ZNF266; KMT2A; SCAI; PRDM4; CNOT2; GSC2; HAND2; RFX1; CREB5; KDM2A; IFNB1; ZNF292; ZNF177; SALL2; PAX9; POU4F3; ZNF142; SOX3; BARX1; MLLT1; ZNF778; RFX3; TLX2; TSG101; BANP; HOXA4; RBBP5; ZSCAN32; MSX2; ZNF407; TRIM33; ZSCAN16; GBX2; GTF2A1; HIVEP1; ZNF225; BRF2; TSC22D3; ZNF140; ZNF155; GCM2; ZNF674; BRDT; SOX1; ZNF44; HOXB1; TLX3; FOXH1; BRD2; LBX1; ZNF154; ZNF91; ZSCAN12; INSM1; ELF2; ZBTB32; HOXD12; NEUROG2; RING1; UIMC1; LHX1; ZNF675; ZNF93; ZNF391; POU2F1; SKIL; ZNF549; CCDC59; POU3F2; IRF1; ZNF473; ATF3; FOXC2; THAP9; ATF4; ZNF234; PCGF1; MSL3; BAZ2A; ZBTB43; ZNF3; NONO; SIX2; ZNF671; TCF25; BCL11A; CDIP1; ESR2; TCEB2; HESX1; ZNF254; CALCOCO1; ZNF682; ZFP69B; CCNT1; ZNF304; ZBTB39; LDB1; ZNF80; ZSCAN9; GLI2; ZNF780B; ZNF81; SHOX2; UBE2B; TSHZ2; NR2C1; ARID5A; ING4; MAPK8IP1; CIITA; ERCC3; ZNF14; SIM1; CERS6; MYT1; KDM4A; ZNF467; ATOH1; ZNF415; ZNF394; EMX2; PRDM10; PAX8; POU6F2; WNT4; NFIX; PITX3; HCFC2; TRAF6; ZNF133; MEF2D; ZNF23; ZNF506; ZNF516; HEY2; ELF4; TAF11; RYBP; SIRT7; ZNF468; ZNF334; ZNF184; LYL1; PHOX2A; WT1; ZNF410; GBX1; NFRKB; ZNF227; ACTL6B; PEG3; BAZ2B; ZNF345; ZNF34; FEZF2; ZNF76; HIPK1; IRF7; PRDM2; ING3; ZMYM2; POU1F1; ZNF205; ZNF211; BLZF1; MEIS1; PSPC1; RCOR3; MED23; MYCN; ATF2; SUPT4H1; RBM39; CAMTA1; HSF2; NR2E1; SOX21; CSDC2; ZNF223; ZNF257; CITED1; ZNF24; ZNF224; ZNF493; ZFY; SETDB1; KAT6B; SOX18; IRF4; CBFA2T2; ZNF529; ARID4A; IRF9; KAT5; JUND; HDAC9; ZNF232; ZNF287; PNRC1; PAX6; CBX4; SOX12; ZNF45; AFF2; RNF10; TOX4; SALL1; ZNF430; HOXC5; SIX3; BTG1; PAWR; STAT2; NPM1; ARID3B; GON4L; ZKSCAN7; ZNF358; RUNX3; CHD3; ZHX2; ZNF688; MNDA; SPDEF; EVX1; PGR; PBX2; CERS4; ZNF83; MDM4; YAF2; ZNF141; JUNB; ZNF85; NRBF2; CBX7; ZNF43; ZNF432; ZNF331; ADNP2; PKNOX2; TDP2; NR1H4; BRD8; MEIS2; ZZZ3; ZNF667; NFE2; TMF1; CREB3L1; TLE2; ZBTB17; ENY2; YEATS2; ZSCAN31; CARF; MTF2; ZNF350; ANKRD1; RORA; HDAC3; PHIP; BACH2; CEBPG; LHX2; KDM5A; MZF1; NR4A2; ARID4B; CHD1; TOPORS; PLAGL1; PPARGC1A; GLI3; GATA1; SP100; ZFHX4; SP2; COPS2; NFATC4; KLF11; PEX2; CTR9; DBP; ZNF419; TFDP2; INSR; CITED2; ZNF423; MYT1L; ZNF268; PBXIP1; FLI1; EYA1; BCL3; ASCL1; ZNF611; MSX1; DACH1; SMARCD3; RBBP8; FOXA1; MEOX1; ZIC3; BIRC2; NFAT5; HOXD1; SIX1; ZNF117; ZIC1; BCL6; JARID2; CREBZF; SPIB; TOX; DLX2; TERF1; RFX5; LIN28A; NCOA2; STAT4; AFF1; BRD4; ZNF165; LEF1; HMGN3; PCGF2; HOXC10; ZNF721; REPIN1; FOXN3; LPIN2; TRIB3; CBFA2T3; PAX5; MYCL; ESR1; SOX11; HOXD3; EYA2; CREB1; CRYM; ZNF264; AEBP1; DLX5; CREG1; PDLIM1; NCOA3; MEOX2; NEUROD1; ERBB4; TLE4; HOXB2; GATA6; TWIST1; TBX2; MAFB
Down-regulation 120 MYCBP; RUVBL1; HMGA2; FOSL1; CENPF; MYC; ATF6; CCNA2; TFDP1; MKL2; PARP1; DNMT1; SMAD3; SUV39H1; ATF1; CBFB; HNRNPD; FOXM1; CDK2; YWHAB; ELK3; NUP62; MYBL2; PTRF; BRD3; CALR; RHOA; WHSC1; RBBP4; BRCA1; GTF2I; BRD7; WWTR1; PMS1; HMGB2; SMARCC1; ECD; RBL1; MYBL1; C1QBP; PRKDC; NR3C1; RBM14; DEK; TCEA2; ZNF512B; SOX9; CBX5; ZBED4; KLF9; DRAP1; ETS2; PA2G4; AHR; HMGB3; NCOR2; PTTG1; ENO1; SUB1; URI1; TRRAP; TCF12; PPRC1; CDYL; BAZ1A; SFPQ; HDGF; NRIP1; SMAD1; CHD9; ERG; RUVBL2; TRIM32; BCLAF1; MLXIP; XRCC6; CENPB; SLC2A4RG; FOXK2; SNAI2; FLNA; SMAD2; WWC1; ID1; ZFP36L2; LIMD1; AGO2; FOXD1; CCNE1; ATF5; CTNNB1; TRIM16; BMI1; LOXL2; JUN; ZNF652; KLF5; ADRB2; MED24; HOXB7; BHLHE40; NFIB; PURA; HMGA1; SAP30; ZNF22; EGR2; TBL1XR1; IFI16; PPARG; RBPMS; PUF60; TRIM29; HEY1; KLF6; NR2F1; SSBP2; LMCD1; ID4; THAP11