Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID11404 Azd-5438 GSE70138 HME1 Human 24h 3.33uM EID0014
Types Number Response transcription factors
Up-regulation 476 HDAC9; PRDM2; TGIF2; HOXB1; NFIX; ZNF324B; ZNF3; IKZF3; VENTX; HIC1; BCL11A; ZNF142; NR3C1; FOXB1; GCM1; SCRT1; MEF2C; RBPJL; CDX4; PRDM9; PAX3; MYT1; SIX3; RFX1; PRDM16; CRX; ETV2; NEUROG2; SNAPC4; HOXD12; MLLT1; ZNF408; ZNF195; ZNF154; PRDM12; NR5A1; FOXH1; ZKSCAN4; PAX1; ZNF778; MAK; POU2F3; ZNF669; ZNF34; BANP; POU3F4; GLI2; GRIP1; PDX1; RFX3; TULP1; POU4F3; CIITA; EMX1; ACTL6B; MAFG; TAF4B; HES2; SOX17; GBX2; MSX2; GMEB2; SOX1; ZNF423; LDB1; ZNF749; DOT1L; POU6F2; CHD2; E2F5; HOXA2; HOXA6; BRD4; UTF1; CAMTA2; FOXD3; ZNF257; ZNF415; POU2F1; FOXE3; GATAD2A; THRB; CDIP1; BARX1; LHX1; ZNF639; ZNF324; SOX21; HAND1; ETV3; ONECUT2; ZNF79; DMRT1; ZNF787; TLX2; SOX14; CBX2; ZSCAN12; ZNF334; SOHLH2; ZNF771; IFNB1; GSC2; NACA2; TLX3; L3MBTL1; SRY; ZNF232; HOXB8; ZNF157; ZNF549; VHL; TEF; GCM2; MYCL; ATOH1; ZNF155; LBX1; ZSCAN16; ZNF35; ZNF132; ALX4; ZNF221; SKIL; LIN28A; FEZF2; NR2C2; HOXA4; ZNF816; RSF1; ZNF391; ZNF667; ZNF407; ZNF225; NHLH2; SOX12; ZNF202; MAPK8IP1; ESRRB; SOX2; WT1; ZNF550; ZNF80; ZNF222; FOXP3; ZNF215; ZNF780B; PPARD; ZNF81; TBR1; OVOL2; MED31; NEUROD4; MTF1; ZNF814; ZNF174; TBX10; PPARA; ZNF14; TFEC; ZIM2; SMAD7; CCNH; SOX15; ZNF536; RLF; ZNF613; ZNF682; NKX6-1; ESR1; ZIC4; ZNF235; SOX3; EMX2; ZNF91; POU1F1; ZNF74; ZNF208; ZNF440; ZNF471; ZSCAN9; ZNF304; BACH2; SOX18; SP140; EBF2; DLX6; ZNF211; MAML3; ZNF467; PEG3; PPRC1; FOXK2; TCEA2; ZNF273; NFATC4; ZNF239; ZNF675; RXRG; ZNF674; AFF3; ASXL1; HIC2; PRDM14; ZBTB48; ZNF500; ZNF362; ZNF506; PAX4; DDIT3; MYF5; SIRT7; THAP4; DACH1; NFKB2; NEUROD1; ZNF133; TBX5; VAX2; PKNOX2; KLF8; SALL2; MECP2; ZXDB; RING1; GON4L; RELA; LHX3; HINFP; AR; KLF15; MYNN; ZKSCAN8; TULP2; PRDM5; BNC1; ZNF136; SETDB1; ELF4; ZFP37; ZNF696; FOXO4; ZIC3; ZNF350; SP4; WIZ; EYA1; TP73; ZNF562; ZNF557; HNF1B; C1QBP; ZNF512B; KDM4C; HESX1; MDM4; EN2; POU3F2; HEYL; ZNF93; ZFY; BRDT; RNF138; ZNF460; PAX2; WWC1; PHOX2A; ZZZ3; ZNF10; LHX6; CREB5; ZNF7; HIF3A; CRTC1; ARID3B; CIR1; SOX5; ZNF688; GBX1; NEUROG1; PAX6; RELB; HEY2; HIPK2; CBFA2T3; CSDC2; HIRA; NANOG; ZNF695; ZFPM2; SNAI1; ZNF492; TRAK1; VGLL1; MEOX1; ZNF671; NKX3-2; ZNF654; BTF3; SERTAD2; TDP2; ZBED2; EP300; TGS1; KLF13; ZNF23; TOX; CHD7; ZNF223; ZNF444; DLX4; ERCC3; ZNF8; ZNF606; ZNF426; ZNF573; TBX19; SKI; ZNF835; ZNF331; NR2E1; FEV; ZNF571; CNBP; TAF1A; NEUROD2; ZNF770; IRF8; THRA; ZNF711; DCC; SUPT5H; CAMTA1; NR0B2; ZNF556; ZNF165; ERBB4; TEAD3; TOX4; SIN3B; EGR4; CBFA2T2; ZNF43; ZNF419; HIVEP2; RORA; ZNF254; AFF4; ZNF529; ZNF345; CEBPA; ISL1; MYCN; FOS; OSR2; IRF1; HLF; NR5A2; ZFP2; ZNF248; MZF1; MXI1; SP2; OVOL1; CEBPG; ZNF124; ZNF358; ETV6; PROP1; TCF21; PRPF6; CUX2; YEATS2; INSM1; RARG; IRF6; ZNF135; PHF20; FOXO3; ZNF701; NHLH1; ZXDC; TBX21; SUPT4H1; NKX2-1; ZNF224; TFAP2A; HNF4G; SPEN; ZNF141; MEIS2; PFDN5; HOXD3; GATA1; SSBP3; ZNF264; HOXB13; ZHX2; ANKRD1; KAT8; ZNF267; SOX11; ZNF266; ZNF85; SOX13; KLF11; POU5F1B; PLAGL1; TAF11; FOXJ1; ZNF544; RUNX3; TRIB3; ZKSCAN7; CREB1; CCNC; BRD2; SMARCD3; FOXA1; HMBOX1; CEBPZ; ZIC1; CCNE1; SPDEF; HOXD1; STAT4; REPIN1; E2F3; CBX7; RYBP; ZNF432; ZNF611; ZNF117; TCF4; HEY1; CERS4; NFKBIA; NR0B1; VPS72; CREBZF; FOSB; ZNF329; FOXJ3; EN1; TWIST1; ZNF665; HOXB5; BNC2; SHOX2; ARNT2; NFATC1; BHLHE40; JUP; ASCL1; PCGF2; DAXX; CEBPD; FOXG1; CREG1; ATF3; MECOM; MEIS1; RFX5; CTBP2; COPS2; E2F2; POU2AF1; DLX5; KLF10; PAX5; SOX9; MAFB; BHLHE41; IKZF1; NR2F6; GATA3
Down-regulation 97 CCNA2; CENPF; HDAC6; HMG20B; RB1; ATF6; BRCA1; EDF1; BLM; HES1; ECD; TCF12; PHF2; BRD3; ATF1; PSIP1; GTF2A2; CALR; SMARCA2; CHAF1B; ARNTL2; PBRM1; RBBP4; SMARCC1; FOXD1; TAF9B; RNF14; FOXM1; HOXB7; BCLAF1; HMGB1; HMGB2; NELFB; ATF5; HOXC6; CARHSP1; NR4A1; MXD4; BRIP1; PRKDC; TRIM32; SMAD3; AES; PSMC3; MED14; PTTG1; SMARCE1; WHSC1; ZBTB16; DNAJC1; AHR; SUV39H1; SAP30; CBFB; MAGED1; PQBP1; RBBP7; MTDH; RNF141; MED23; NCOR2; TCEB2; LOXL2; EGR1; TCFL5; BMI1; CBX3; NFE2L1; NCOA1; ENO1; PURA; ZNF32; CHD9; HTATIP2; NR2F2; WWTR1; DDX5; SREBF1; ZBTB38; NR1D2; HLTF; ZEB1; JUNB; HMGB3; HOXC10; IFI16; TBL1XR1; LEF1; TRIM29; FLNA; TLE4; NKX3-1; FOXC1; MYBL1; SSBP2; TXNIP; IKBKAP